ISSN 1746-0751 Regen. Med. (2012) 7(3), 1–5 1 10.2217/RME.12.9 © 2012 Future Medicine Ltd A successful cell therapy industry is extremely important to the UK economy because it offers significant benefits to patients and to the National Health Service and because it provides an opportunity to grow a knowledge-based industry that can remain largely local. There are currently 26 cell therapy comp...

Incentive salience is a motivational magnet property attributed to rewardpredicting conditioned stimuli (cues). This property makes the cue and its associated unconditioned reward ‘wanted’ at that moment, and pulls an individual’s behavior towards those stimuli. The incentive-sensitization theory of addiction posits that permanent changes in brain mesolimbic systems in drug addicts can amplify ...

Transit travel time and operating speed influence service attractiveness, operating cost, and system efficiency. The objective of this paper is to estimate the values of parameters that affect the total travel time for a particular bus route in Portland, Oregon. The Metropolitan Transportation District of Oregon ~TriMet! provides transit service in the three-county Portland metropolitan area. T...

Several lines of research are converging on the idea that emotion regulation is an essential component of mental health and that problems of regulation are associated with a variety of forms of psychopathology (Cicchetti, Ackerman, & Izard, 1995; Davidson, 2000; Gross, 1998). Emotions involve changes in subjective experience, expressive behavior, and physiological responses; emotion regulation ...

It has been hypothesized that the planktonic community of the North Pacific subtropical gyre (NPSG) underwent a ‘‘domain shift’’ in the early 1980s in which phytoplankton of the domain Eukarya were supplanted by phytoplankton of the domain Bacteria, primarily Prochlorococcus. P limitation of eukaryotic phytoplankton was implicated as the causative chemical factor in the domain shift, and we sou...

The ∼70 unidentified sources of the EGRET sky survey may be one of its most important legacies. The identification of these sources at other wavelengths is critical to understanding their nature. Many have flat spectra out to 10 GeV which, if extrapolated to TeV energies, would be easily detectable relative to the steeply falling diffuse background. The Whipple Observatory γ-ray telescope has b...

People feel grateful when they have benefited from someone’s costly, intentional, voluntary effort on their behalf. Experiencing gratitude motivates beneficiaries to repay their benefactors and to extend generosity to third parties. Expressions of gratitude also reinforce benefactors for their generosity. These social features distinguish gratitude from related emotions such as happiness and fe...

Stochastic selection models provide sharp predictions about equilibrium selection when the noise level of the selection process is taken to zero. The difficulty is that, when the noise is extremely small, it can take an extremely long time for a large population to reach the stochastically stable equilibrium. An important exception arises when players interact locally in small close-knit groups...

Cutaneous squamous cell carcinoma (cSCC) is a malignant neoplasm of the skin resulting from accumulation somatic mutations due to solar radiation. cSCC one fastest increasing malignancies, and it represents particular problem among immunosuppressed individuals. MicroRNAs are short noncoding RNAs that regulate expression protein-coding genes at post-transcriptional level. In this study, we ident...