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We investigate the lead-lag relationship between growth of patent applications, growth of R&D, and growth of total sectoral employment for 270 German labour market regions over the period 1999-2005. Our unique panel dataset includes information on four two-digit industries, namely Chemistry, Transport equipment, Medical & Optical Equipment as well as Electrics & Electronics. The results obtaine...
Srinivasulu Aitipamula, Gautam R. Desiraju,* Mariusz Jaskólski,* Ashwini Nangia* and Ram Thaimattam School of Chemistry, University of Hyderabad, Hyderabad 500 046, India. E-mail: [email protected]; [email protected] Center for Biocrystallographic Research, IBCh, Polish Academy of Sciences and Department of Crystallography, Faculty of Chemistry, A. Mickiewicz University, Grunwaldzka 6, ...
Madhavan Jaccob , Gopal Sabapathi, J Vijaya Sundar, P Kolandaivel *, V Subramanian * & Ponnambalam Venuvanalingam * Theoretical and Computational Chemistry Laboratory, School of Chemistry, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India Email: [email protected] Chemical Laboratory, CSIR-Central Leather Research Institute, Adyar, Chennai 600 020, Tamil Nadu, India Ema...
Clostridium difficile is the commonest cause of antibiotic-associated diarrhoea, with the hospitalized elderly being at particular risk. The organism makes a crystalline surface protein layer (S-layer), encoded by the slpA gene, the product of which is cleaved to give two mature peptides which associate to form the layer. The larger peptide (high molecular weight; HMW), derived from the C-termi...
A series of diaryl- and fluorenone-based analogs of the lead compound UA-62784 [4-(5-(4-methoxyphenyl)oxazol-2-yl)-9H-fluoren-9-one] was synthesized with the intention of improving upon the selective cytotoxicity of UA-62784 against human pancreatic cancer cell lines with a deletion of the tumor suppressor gene deleted in pancreas cancer locus 4 (DPC-4, SMAD-4). Over 80 analogs were synthesized...
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