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Introduction PFAPA syndrome (acronym for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis) is the most common cause of periodic fever in childhood. It is considered part of the wide family of the autoinflammatory diseases, but a genetic or molecular marker hasn’t been identified yet, therefore, its etiology is still unknown. Diagnosis is essentially based on clinical crite...
BACKGROUND Afghanistan has struggled with several decades of well-documented conflict, increasing the importance of providing emergency services to its citizens. However, little is known about the country's capacity to provide such care. METHODS Three native-speaking Afghan-American physicians performed an assessment of emergency care via combined quantitative and qualitative survey tools. Ho...
Positive modulators of the excitatory amino acid receptor a-Amino-3hydroxy-5-methyl-4-isoxazole Propionate (AMPA) has been shown to enhance memory and learning tasks performed by rodents and by human subjects. A new class of AMPA receptor modulators has been recently synthesized. These compounds belong to the class of organic nitrate ester of the nitroglycerine family and are designated GT-2 1-...
BACKGROUND This study examines associations between perceptions of neighbourhood environment and physical activity and sports within Portuguese adolescents. METHODS The sample consisted of 4,877 individuals of both genders, with an average age of 14 years. The instrument used was the Health Behavior School-aged Children questionnaire. RESULTS Perceptions of the neighbourhood being unsafe fo...
Although it is clear that KIR3DL1 recognizes Bw4(+) HLA-B, the role of Bw4(+) HLA-A allotypes as KIR3DL1 ligands is controversial. We therefore examined the binding of tetrameric HLA-A and -B complexes, including HLA*2402, a common Bw4(+) HLA-A allotype, to KIR3DL1*001, *005, *007, and *1502 allotypes. Only Bw4(+) tetramers bound KIR3DL1. Three of four HLA-A*2402 tetramers bound one or more KIR...
A number of research systems have demonstrated the benefits of accompanying each request with a machine-checkable proof that the request complies with access-control policy — a technique called proof-carrying authorization. Numerous authorization logics have been proposed as vehicles by which these proofs can be expressed and checked. A challenge in building such systems is how to allow delegat...
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