The impact of repeated administration cinntamtannin A2 (A2, 25 μg/kg) on skeletal muscle disuse atrophy model mice induced by hindlimb suspension for 14 days was examined. In soleus, weight loss and a reduction in the average myofibre size with shifting to smaller side peak were observed suspension-vehicle group, but reduced these changes. Average significantly increased ground-A2 compared grou...

Four reduced-height (5 m) BS 8414-1 façade flammability tests were conducted, three having mineral-filled aluminium composite material (ACM-A2) with polyisocyanurate (PIR) and phenolic (PF) foam stone wool (SW) insulation, the fourth polyethylene-filled ACM (ACM-PE) PIR insulation. Each was constructed from a commercial engineer’s design, built by practising installers. The ACM-PE/PIR burnt so ...

syntax n ∈ Num x ∈ Var a ∈ Aexp a ::= n | x | a1 + a2 | a1 * a2 | a1 a2 Semantic domains Integer = {... -3, -2, -1, 0, 1, 2, 3 ...} Truth-Value = {true, false} State = Var → Integer Semantic valuation functions N: Num → Integer A: Aexp → State → Integer A [[n]] = λs. N [[n]] A [[x]] = λs. s x A [[a1 + a2]] = λs. A [[a1]] s + A [[a2]] s A [[a1 * a2]] = λs. A [[a1]] s * A [[a2]] s 6 Prolog and Au...

Antiphospholipid (aPL) antibodies recognize receptor-bound beta(2) glycoprotein I (beta(2)GPI) on target cells, and induce an intracellular signaling and a procoagulant/proinflammatory phenotype that leads to thrombosis. Evidence indicates that annexin A2 (A2), a receptor for tissue plasminogen activator and plasminogen, binds beta(2)GPI on target cells. However, whether A2 mediates pathogenic ...

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Bleomycins, a group of glycopeptide antibiotics differ from one another in their terminal amine moieties. 14C-Methyl-labeled 3-aminopropyl-dimethylsulfonium was confirmed to be incorporated into the amine moiety of bleomycin A2. Addition of amines of bleomycin A2, A2'-a, A2'-b, A2'-c, A5, B2 and B4 to fermentation media increased the rate of production of the bleomycin which contained the added...

The A2 genes of Leishmania donovani encode amastigote-specific A2 proteins, which are considered to be virulence factors required for the survival of this protozoan parasite in the mammalian host. The A2 genes are present within a multigene family and corresponding A2 proteins are composed predominantly of multiple copies of a 10 amino acid repeat sequences. A2-specific antibodies have been det...

early in the development of many animals, before transcription begins, any change in the pattern of protein synthesis is attributed to a change in the translational activity or stability of mrna in the egg and early embryo. as a result, translational control is critical for a variety of developmental decisions, including oocyte maturation and initiation of preimplantation development. in this s...