objective: to compare the efficacy of emla cream and lidocaine injection to reduce pain during episiotomy repair. materials and methods: a total of 46 primiparous women with normal pregnancy who referred for normal vaginal delivery and needed episiotomy repair were selected and randomly divided into two groups. for emla group, one hour before the estimated time of delivery, 5g of emla cream was...

The author's study demonstrates that application of EMLA cream to treatment sites significantly reduces needle pain during Botox administration. Twenty patients receiving 200 Botox injections in the glabellar area experienced a 60% reduction in pain in EMLA-pretreated sites compared with that in matched control sites.

AIM To assess the safety and efficacy of EMLA cream (eutectic mixture of local anaesthetics) used to induce surface anaesthesia for venepuncture in healthy preterm infants. METHODS Nineteen infants, median gestational age 31 weeks (range 26-33 weeks) were assessed in a randomised, double blind, placebo controlled, cross-over trial. Changes in physiological variables (heart rate, blood pressur...

We dissected the relative contribution of arteriovenous hemodynamics, the venoarteriolar response (VAR), and the myogenic reflex toward a decrease in local blood flow induced by venous congestion. Skin blood flow (SkBF) was measured in 12 supine subjects via laser-Doppler flowmetry 1) over areas of forearm and calf skin, in which the VAR was blocked by using eutectic mixture of local anesthetic...

Temporary deafferentation of the upper limb, with ischemic or anesthetic nerve block, has rapid effects on sensorimotor cortex. Cutaneous anesthesia of the forearm has recently been found to improve sensory and motor function of the paretic hand in chronic stroke patients. However, the neurophysiological mechanisms are unknown. The aim of this study was to investigate the behavioral and neuroph...

OBJECTIVE To investigate the efficacy and safety of dorsal penile nerve block (DPNB) and eutectic mixture of lidocaine (EMLA) for palliation of pain associated with circumcision in low-birth-weight infants. DESIGN Randomized, blinded, controlled trial. SETTING Intensive care nursery (step down unit) at Georgetown University Medical Center, Washington, DC. PARTICIPANTS Fifty neonates with ...

The analgesic effect and the usefulness of EMLA cream 5% in connection with venous blood-sampling was investigated in 42 Tanzanian schoolchildren. Approximately 2.5 g EMLA was applied to the right cubital fossa for a minimum of 120 min. The analgesic effect was pronounced--93% of the venepunctures were pain-free and no child experienced severe pain. No adverse reactions were observed and the ch...

1. de Waard-van der Spek FB, Mulder PG, Oranje AP. Prilocaine/lidocaine patch as a local premedication for skin biopsy in children. J Am Acad Dermatol. 1997; 37(3, pt 1):418-421. 2. Buckley MM, Benfield P. Eutectic lidocaine/prilocaine cream: a review of the topical anaesthetic/analgesic efficacy of a eutectic mixture of local anaesthetics (EMLA). Drugs. 1993;46(1):126-151. 3. Hoss DM, Gross EG...