نتایج جستجو برای: ژن edar
تعداد نتایج: 15984 فیلتر نتایج به سال:
Hypohidrotic ectodermal dysplasia (HED) is a rare genetic disorder caused by mutation in either the ectodysplasin (EDA), A receptor (EDAR), EDAR associated via death domain (EDARADD), or Wnt family member 10A (WNT10A) genes that result impaired development of ectodermal-derived structures. The literature defines two types dysplasia, which are hypohidrotic and hidrotic. X‐linked (XLHED), also kn...
AbstrAct The continuous K nearest neighbor (CKNN) query is an important type of query that finds continuously the KNN to a query point on a given path. We focus on moving queries issued on stationary objects in Spatial Network Database (SNDB) The result of this type of query is a set of intervals (defined by split points) and their corresponding KNNs. This means that the KNN of an object travel...
Hypohidrotic ectodermal dysplasia (HED) is the most prevalent type of ectodermal dysplasia (ED). ED is an umbrella term for a group of syndromes characterized by missing or malformed ectodermal structures, including skin, hair, sweat glands, and teeth. The X-linked recessive (XL), autosomal recessive (AR), and autosomal dominant (AD) types of HED are caused by mutations in the genes encoding ec...
The development of ectodermal organs requires signalling by ectodysplasin (Eda), a tumor necrosis factor (TNF) family member, its receptor Edar and downstream activation of the nuclear factor kappaB (NF-kappaB) transcription factor. In humans, mutations in the Eda pathway components cause hypohidrotic ectodermal dysplasia, a syndrome characterized by missing teeth, sparse hair and defects in sw...
The Sonic hedgehog (Shh) signaling pathway regulates developmental, homeostatic, and repair processes throughout the body. In the skin, touch domes develop in tandem with primary hair follicles and contain sensory Merkel cells. The developmental signaling requirements for touch dome specification are largely unknown. We found dermal Wnt signaling and subsequent epidermal Eda/Edar signaling prom...
Ectodermal contribution to the induction of pharyngeal teeth that form in the endodermal territory of the oropharyngeal cavity in some teleost fishes has been a matter of considerable debate. To determine the role of ectodermal cell signaling in scale and tooth formation and thereby to gain insights in evolutionary origin of teeth, we analyzed scales and teeth in rs-3 medaka mutants characteriz...
Abstract This research note presents evidence for the oldest Middle Pleistocene Eastern Saharan human activity from area referred to as Desert Atbara River ( EDAR ), Sudan, which is currently threatened by gold mining. Preliminary results of multifaceted analyses indicate Homo sapiens during MIS 5 well erectus 7–11 or earlier.
: Hypohidrotic ectodermal dysplasia (HED) is the most common type of that result faulty development leading to such defects as hypotrichosis, anodontia or hypodontia, and hypohidrosis anhidrosis. X-linked HED caused by mutations in ectodysplasin A (EDA) gene accounts for 90% all cases. Autosomal other involved genes, EDA-receptor (EDAR) gene. In this study, we included two distinct families wit...
Hair morphology is highly differentiated between populations and among people of European ancestry. Whereas hair morphology in East Asian populations has been studied extensively, relatively little is known about the genetics of this trait in Europeans. We performed a genome-wide association scan for hair morphology (straight, wavy, curly) in three Australian samples of European descent. All th...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید