There is currently a regain of interest in the Alternating Direction Implicit (ADI) algorithms as preconditioners for iterative methods for solving large sparse linear systems, because of their suitability for parallel computing. However, the classical ADI iteration is not directly applicable to Finite Element (FE) matrices, tends to converge too slowly for 3-D problems, and the selection of ad...

INTRODUCTION Currently available clinical assays to detect antiphospholipid antibodies (aPL) test for IgG and IgM antibodies to cardiolipin (aCL) and β2-glycoprotein I (aβ2GPI). It has been suggested that testing for IgA aPL and for antibodies to Domain I (DI), which carries the key antigenic epitopes of β2GPI, could add value to these current tests. We performed an observational, multicenter c...

OBJECTIVE To examine the clinical presentations and management of patients presenting to an accident and emergency (A&E) department with an AIDS defining illness (ADI). METHODS Presentations of patients in the A&E department with ADI were reviewed retrospectively. The age, sex, ethnic origin, risk factor for HIV infection, route of referral to hospital, presenting complaint, triage category, ...

We give a highly efficient, accurate and unconditionally stable algorithm to solve the partial differential equation for simulating the action potential propagation through cardiac tissue. In the new algorithm, we discretize the space domain by combining a compact finite difference scheme with an alternating direction implicit (ADI) scheme, which has fourth-order accuracy for interior mesh poin...

Arginine decarboxylase (encoded by adi) is induced under conditions of acidic pH, anaerobiosis, and rich medium. The DNA sequence of a 3-kb fragment of the Escherichia coli chromosome encoding biodegradative arginine decarboxylase was determined. This sequence encodes a protein of 755 amino acids with a molecular size of 84,420 daltons. The molecular weight and predicted Adi amino acid composit...

We present the first order error bound for the Lyapunov equation AX +XA∗ = −GG∗, where A is perturbed to A+ δA. We use the structure of the solution of the Lyapunov equation X = m ∑ k=1 WkW ∗ k , where Wk is the k-th matrix obtained by the Low Rank Cholesky Factor ADI (LRCF-ADI) algorithm using the set of ADI parameters equal to exact eigenvalues of A, that is with ADI parameters {p1, . . . , p...

We present a multilevel high order ADI method for separable generalized Helmholtz equations. The discretization method we use is a 1-D fourth order compact nite di erence applied to each directional component of the Laplace operator, resulting a discrete system e ciently solvable by ADI methods. We apply this high order di erence scheme to all levels of grids, and then starting from the coarses...

The protozoan parasite Giardia lamblia uses arginine deiminase (ADI) to produce energy from free L-arginine under anaerobic conditions. In this work, we demonstrate that, in addition to its known role as a metabolic enzyme, it also functions as a peptidylarginine deiminase, converting protein-bound arginine into citrulline. G. lamblia ADI specifically binds to and citrullinates the arginine in ...

Melanomas and other cancers that do not express argininosuccinate synthetase (AS), the rate-limiting enzyme for arginine biosynthesis, are sensitive to arginine depletion with pegylated arginine deiminase (ADI-PEG20). However, ADI resistance eventually develops in tumors because of AS upregulation. Although it has been shown that AS upregulation involves c-Myc, the underlying mechanisms remain ...