Starting from the framework of Product Lifecycle Management (PLM), sustainability should be provided by continuous sharing of information among the different product lifecycle phases. A PLM system provides lifecycle knowledge generated by PLM systems through product lifecycle activities. The paper aims at presenting how PLM systems represent a very important foundation for achieving a more sust...

This paper introduces a concept applied for a new PLM-supported process in steam turbine service business. The concept has been developed and instantiated in an industrial case: The paper starts with an analysis of engineering processes and the IT landscape in a globally acting company offering MRO (Maintenance, Repair and Overhaul) services for steam turbines. Illustrations show how digital pr...

FXYD PROTEINS COMPRISE a family of small integral membrane proteins that are regulators of ion transport (15). FXYD proteins have an extracellular NH2 terminus containing the signature PFXYD motif, a single transmembrane (TM) domain, and a cytoplasmic COOH terminus. They are distributed either in excitable tissues or organs involved in solute and fluid transport. Members in the FXYD family are ...

Product Lifecycle Management (PLM) solutions have been serving as the basis for collaborative product definition, manufacturing, and service management in many industries. They capture and provide access to product and process information and preserve integrity of information throughout the lifecycle of a product. Efficient growth in the role of Building Information Modeling (BIM) can benefit v...

Previous studies showed increased phospholemman (PLM) mRNA after myocardial infarction (MI) in rats (Sehl PD, Tai JTN, Hillan KJ, Brown LA, Goddard A, Yang R, Jin H, and Lowe DG. Circulation 101: 1990-1999, 2000). We tested the hypothesis that, in normal adult rat cardiac myocytes, PLM overexpression alters contractile function and cytosolic Ca(2+) concentration ([Ca(2+)](i)) homeostasis in a m...

A major challenge of any product engineering project is to support the creation, exchange, management and archival of information about product, process, people and services across the networked and extended enterprise covering the entire product lifecycle spectrum. An information support system for Product Lifecycle Management (PLM) requires a move from product data exchange to product informa...

12 T he significance of periodic limb movements in sleep (PLMS) in the absence of Restless Legs Syndrome (RLS) or Periodic Limb Movement Disorder (PLMD), has been a controversial issue in recent years. Nevertheless, based on evidence gathered in recent years on the associations and consequences of PLMS, the issue needs to be reconsidered.Here it shall be demonstrated, that PLMS are associated w...

The objective of this article is to show that SEAMLESS, a designed and developed method from PCO Innovation, allows improving PLM approach efficiency by proposing to set up a business/Information System referential. PLM, as a PLM solution, is a software which basically supports product conception and product industrialization business processes (and potentially other upstream and/or downstream ...

Commercial off-the-shelf (COTS) Product Lifecycle Management (PLM) systems have been introduced by companies to facilitate their new product development process to shorten the product time to market, reduce the product development cost, and meet the dynamic demands of customers. However, PLM implementation is not an easy job and some of the attempted projects failed. A common problem encountere...

BACKGROUND Periodic leg movements (PLM) during sleep consist of involuntary periodic movements of the lower extremities. The debated functional relevance of PLM during sleep is based on correlation of clinical parameters with the PLM index (PLMI). However, periodicity in movements may not be reflected best by the PLMI. Here, an approach novel to the field of sleep research is used to reveal int...