Eosinophil granule major basic protein (MBP), a potent toxin for helminths and mammalian cells in vitro, is a single polypeptide chain rich in arginine. MBP has been localized on damaged helminths and tissues in hypersensitivity diseases including bronchial asthma. The MBP cDNA indicates that MBP is translated as a slightly acidic preproprotein with an acidic propart. To test the hypothesis tha...

Maltose-binding protein (MBP) is essential for maltose transport and chemotaxis in Escherichia coli. To perform these functions it must interact with two sets of cytoplasmic membrane proteins, the MalFGK transport complex and the chemotactic signal transducer Tar. MBP is present at high concentrations, on the order of 1 mM, in the periplasm of maltose-induced or malTc constitutive cells. To det...

Objectives: To clarify whether bowel preparation use or its individual components [mechanical bowel preparation (MBP)/oral antibiotics] impact specific outcomes after colorectal surgery. Methods: National Surgical Quality Improvement Program–targeted colectomy data initiated in 2012 capture information on the use/type of bowel preparation and colorectal-specific complications. For patients unde...

An experimental allergic encephalomyelitis was induced by bovine myelin basic protein (MBP) and bovine galactocerebroside (GC) on male guinea pigs. Animals were divided into five experimental and one control groups. Among the five experimental groups, three were inoculated with 75 micrograms, 150 micrograms and 300 micrograms of MBP, respectively, to see the dose dependency of demyelination. Th...

Purpose The purpose of this paper is to evaluate the impact on stress and work-related outcomes an app-delivered mindfulness-based program (MBP; Headspace®) offered employees in a UK higher education (HE) institution. Design/methodology/approach Using randomized waitlist control trial design, participants were randomly allocated be (MBP) immediately for 2 months or after waiting list period (WL...

Three custom synthesized myelin basic protein (MBP) peptides, bovine peptide 79-88, human peptide 80-89, and human peptide 82-91, were used to produce four murine monoclonal antibodies (MAb) that were selected on the basis of reaction in a solid phase radioimmunoassay (SRIA) with human MBP. The MAb were compared with respect to antigen specificity against intact MBP and 10 overlapping MBP pepti...

The pathogenesis of multiple sclerosis involves a breakdown in T cell tolerance to myelin proteins like myelin basic protein (MBP). Most MBP-specific T cells are eliminated by central tolerance in adult mice, however, the developmentally regulated expression of MBP allows MBP-specific thymocytes in young mice to escape negative selection. It is not known how these T cells that encounter MBP for...

Abstract Pasta, a staple food worldwide consumed, was fortified with maqui ( Aristotelia chilensis ) berry powder (MBP) and the effect of MBP inclusion evaluated concerning technological, nutritional, sensory properties. Fresh pasta samples were formulated by replacing 0, 7.5, 15 g 100 −1 durum wheat semolina MBP. The did not affect moisture content, but water activity decreased in samples, whi...

MBPConflate is proof-of-concept software developed to aid in conflation research. The program implements a powerful algorithm for automatic multi-source image conflation that utilizes new Algebraic Systems-based similarity metrics during the feature comparison process. One benefit of integrating Algebraic Systems into the feature comparison process is that more global shape properties can be di...

In vivo adoptive transfer of CD4+ T helper cell type 1 clones reactive with autologous myelin basic protein (MBP) may initiate an inflammatory demyelinating disease of the central nervous system called experimental autoimmune encephalomyelitis. Although MBP is also a component of peripheral nervous system (PNS) myelin, previous studies have failed to demonstrate inflammation in the PNS induced ...