Studies of flagellar motility in Chlamydomonas mutants lacking specific central apparatus components have supported the hypothesis that the inherent asymmetry of this structure provides important spatial cues for asymmetric regulation of dynein activity. These studies have also suggested that specific projections associated with the C1 and C2 central tubules make unique contributions to modulat...

Protein kinase D (PKD) isoenzymes regulate the formation of transport carriers from the trans-Golgi network (TGN) that are en route to the plasma membrane. The PKD C1a domain is required for the localization of PKDs at the TGN. However, the precise mechanism of how PKDs are recruited to the TGN is still elusive. Here, we report that ADP-ribosylation factor (ARF1), a small GTPase of the Ras supe...

Plant class III peroxidase (PRX) catalyzes the oxidation and oxidative polymerization of a variety of phenolic compounds while reducing hydrogen peroxide. PRX proteins are classified into apoplast type and vacuole type based on the absence or the presence of C-terminal propeptides, which probably function as vacuolar sorting signals (VSSs). In this study, in order to improve our understanding o...

The cyclic AMP (cAMP) signaling pathway is implicated in the development of alcohol use disorder. Previous studies have demonstrated that ethanol enhances the activity of adenylyl cyclase (AC) in an isoform specific manner; AC7 is most enhanced by ethanol, and regions responsible for enhancement by ethanol are located in the cytoplasmic domains of the AC7 protein. We hypothesize that ethanol mo...

a Department of Biology, Memorial University of Newfoundland, St. John’s, NL, Canada 5 A1B 3X9 6 b Centre for Veterinary Epidemiological Research, Department of Health Management, 7 Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, 8 Charlottetown, Prince Edward Island, Canada C1A 4P3 9 c Department of Mathematics and Statistics, Memorial University of Newf...

We study an eigenvalue problem associated with a reaction-diffusionadvection equation of the KPP type in a cellular flow. We obtain upper and lower bounds on the eigenvalues in the regime of a large flow amplitude A 1. It follows that the minimal pulsating traveling front speed c∗(A) satisfies the upper and lower bounds C1A ≤ c∗(A) ≤ C2A. Physically, the speed enhancement is related to the boun...

Plasma treatment in foals resulted in greater increases in post-transfusion serum IgG concentrations compared with serum treatment. The results of this study suggest that similar foal serum IgG concentrations can be achieved 3 days post-transfusion by administering 1 unit of plasma product or 2–3 units of serum product. Authors’ addresses: Avon Animal Hospital, 45 Morison Dr., Box 2406, Windsor...