Two-year animal carcinogenicity experiments are used to evaluate the potential carcinogenicity from exposure to chemicals. The choice of exposure levels, the allocation of animals to doses, the length of exposure, and the choice of interim sacrifice times all affect the power of statistical tests for carcinogenic effects and the variance of interpolated estimates of carcinogenic risk. In this p...

Introduction Conclusions References

introduction precipitation is one of the most important meteorological variables in comparison with other climatic parameters. it varies extremely over time and space. the occurrence of this climate phenomenon requires specific circumstances in environment. its accurate measurement is important to a wide range of decision makers including hydrologists, agriculturalists, industrialists and etc. ...

Abstract. This paper investigates the global stratospheric Brewer–Dobson circulation (BDC) in ERA5 meteorological reanalysis from European Centre for Medium-Range Weather Forecasts (ECMWF). The analysis is based on simulations of mean age air, including full spectrum, with Lagrangian transport model CLaMS (Chemical Model Stratosphere), driven by winds and total diabatic heating rates. ERA5-base...

Climate change is most pronounced in the northern high latitude region. Yet, climate observations are unable to fully capture regional-scale dynamics due to the sparse weather station coverage, which limits our ability to make reliable climate-based assessments. A set of simulated data products was therefore developed for the North Slope of Alaska through a dynamical downscaling approach. The p...