The tumor microenvironment (TME) is an intricate ecosystem that actively involved in various stages of cancer occurrence and development. Some characteristics biological behavior, such as proliferation, migration, invasion, inhibition apoptosis, immune escape, angiogenesis, metabolic reprogramming, are affected by TME. Studies have shown non-coding RNAs, especially long-chain RNAs microRNAs can...

Myocardial fibrosis is a common pathological feature of various terminal cardiovascular diseases. Progressive the basis for development and progression many cardiac arrhythmias heart failure. There are no effective reversal drugs myocardial due to lack understanding molecular mechanisms. Noncoding RNAs, class RNAs that do not function in coding proteins, have been found be intimately involved l...

Small RNAs constitute a large family of regulatory molecules with diverse functions in eukaryotes. Hallmarks of small RNAs are their dependence on double-stranded RNAs (dsRNA)-specific RNase III-type enzymes for biogenesis and their association with Argonaute family proteins for the silencing process. At least two classes of small RNAs have previously been described: microRNAs (miRNAs) derived ...