We encapsulated tumor necrosis factor-α (TNF-α), a major proinflammatory cytokine, into cholesteryl pullulan (CHP) to prepare TNF/CHP nanoparticles. In this report, we describe the immune-enhancing capability of the nanoparticles to act as a vaccine adjuvant. TNF/CHP nanoparticles showed excellent storage stability and enhanced host immune responses to external immunogens. The nanoparticles wer...

Power and heat are the primary energies for the industry and communities. Combined heat and power (CHP) is a process of heat and power cogeneration, which is designed to meet the needs of both users. In previous studies of emergy analysis on CHP, the transformity was simply calculated by dividing the total emergy input by the amount of production. The result always showed that transformity of e...

Background. The increased practice of traditional Chinese medicine (TCM) worldwide has raised concerns regarding herb-drug interactions. The purpose of our study is to analyze the concurrent use of Chinese herbal products (CHPs) among Taiwanese insomnia patients taking hypnotic drugs. Methods. The usage, frequency of services, and CHP prescribed among 53,949 insomnia sufferers were evaluated fr...

We prepared two types of cholesterol hydrophobically modified pullulan nanoparticles (CHP) and carboxyethyl hydrophobically modified pullulan nanoparticles (CHCP) substituted with various degrees of cholesterol, including 3.11, 6.03, 6.91 and 3.46 per polymer, and named CHP-3.11, CHP-6.03, CHP-6.91 and CHCP-3.46. Dynamic laser light scattering (DLS) showed that the pullulan nanoparticles were 8...

The Combined Heat and Power (CHP) concept is aptly suited to improve or eliminate some of the global and local issues concerning electric commercial buildings. CHP involves on-site or near-site generation of electricity by using gas-fired equipment along with utilization of thermal energy available from the power generation process. CHP has the potential of providing a 30% improvement over conv...

PURPOSE Proliferative vitreoretinopathy (PVR) is characterized by the proliferation and migration of retinal pigment epithelial (RPE) and other cells into the vitreous cavity. The PVR membrane formation also is associated with collagen production by RPE. The authors examined the effect of a proline analog, cis-hydroxyproline (CHP), on proliferation, collagen synthesis, attachment, and migration...

The effect of 4-cis-hydroxy-L-proline (CHP), a proline analogue, on the anchorage-dependent and -independent growth of several transformed rodent cell lines was studied. Mouse NIH-3T3 fibroblasts transformed by a variety of different oncogenes (Ki-ras, mos, src, fms, fes, met, and trk) by a DNA tumor virus (SV40) or by a chemical carcinogen (N-methylnitrosourea) were all found to be more sensit...

Rationale: Cardiac stem cell-derived exosomes have been demonstrated to promote cardiac regeneration following myocardial infarction in preclinical studies. Recent studies have used intramyocardial injection in order to concentrate exosomes in the infarct. Though effective in a research setting, this method is not clinically appealing due to its invasive nature. We propose the use of a targetin...

Combined heat and power (CHP) production is universally accepted as one of the most energy-efficient technologies to produce energy with lower fuel consumption and fewer emissions. In CHP technology, heat and power generation follow a joint characteristic. Traditional CHP production is usually applied in backpressure plants, where the joint characteristic can often be represented by a convex mo...

Although the cost allocation method does not change the total benefits of CHP, the use of various cost allocation methods generally results in significant differences in costs allocated for CHP products. In order to overcome the inadequacy of existing cost allocating methods in theory and in practice, according to the different roles of anergy and exergy in heat supply process of CHP plant, the...