Intraoperative magnetic resonance imaging (MRI) has been proposed as a method to optimize intracerebral targeting and for tracking infusate distribution in gene therapy trials for nervous system disorders. We thus investigated possible effects of two MRI contrast agents, gadoteridol (Gd) and galbumin (Gab), on the distribution and levels of transgene expression in the rat striatum and their eff...

Using the pure spinor formalism, a quantizable sigma model has been constructed for the superstring in an AdS5 × S 5 background with manifest PSU(2, 2|4) invariance. The PSU(2, 2|4) metric gAB has both vector components gab and spinor components gαβ, and in the limit where the spinor components gαβ are taken to infinity, the AdS5 × S 5 sigma model reduces to the worldsheet action in a flat back...

Cardiac hypertrophy represents one of the most central issues in heart failure, involving many aspects of changes in cardiac myocyte from cellular morphology to gene expression and contractile function.1,2 Although the process is at the beginning compensatory in response to hemodynamic load or myocardial injury, cardiac hypertrophy is often followed by pathological remodeling in myocardium and ...

Diffuse groundwater discharge (also known as vertical leakage) forms an important and poorly constrained component of the water balance of the Great Artesian Basin (GAB), Australia’s largest groundwater resource. Around the south-western margin of the GAB, the diffuse leakage from the artesian aquifer discharges into the unconfined water table and subsequently into the atmosphere via evapotrans...

gaz-angubin is a sweet exudate naturally produced by an insect from the gavan-e-gaz-angubin plant. adsorption and desorption isotherms for a gaz-angubin sample were determined at 15° and 25°c over a range of relative humidity from 0 to 90% using a dynamic vapor sorption system. at different levels of relative humidity, changes in sample mass were continuously measured versus time and described ...

Over the past few years, a number of new “fringe” communities, like 4chan or certain subreddits, have gained traction on the Web at a rapid pace. However, more often than not, little is known about how they evolve or what kind of activities they attract, despite recent research has shown that they influence how false information reaches mainstream communities. This motivates the need to monitor...