As is well known, the limitation of single-base real-time kinematic (RTK) GPS carrier phase-based techniques is the constrained distance between base receiver and the rover receiver due to distance-dependent measurement biases. For high productivity GPS surveying techniques, requiring very fast on-the-fly ambiguity resolution, the baseline length is generally restricted to less than 10km. Howev...

Signaling by receptor tyrosine kinases (RTKs) is critical for a multitude of developmental decisions and processes. Among the molecules known to transduce the RTK-generated signal is the nonreceptor protein tyrosine phosphatase Corkscrew (Csw). Previously, Csw has been demonstrated to function throughout the Drosophila life cycle and, among the RTKs tested, Csw is essential in the Torso, Sevenl...

Inter-individual variability causing elevated signaling of receptor tyrosine kinases (RTK) may have hampered the efficacy of targeted therapies. We developed a molecular signature for clustering adult diffuse gliomas based on the extent of RTK pathway activities. Glioma gene modules co-expressed with NF1 (NF1-M), Sprouty (SPRY-M) and PTEN (PTEN-M) were identified, their signatures enabled robus...

This paper presents an overview of technical developments within the CRCSI-funded research on "Delivering Precise Positioning Services in Regional Areas" undertaken by the authors since mid-2007. The research aims to address the technical and business issues that currently constrain GPS-based local area RTK precise positioning services so as to operate in future across larger regional areas, an...

Receptor tyrosine kinases-based autocrine loops largely contribute to activate the MAPK and PI3K/AKT pathways in melanoma. However, the molecular mechanisms involved in generating these autocrine loops are still largely unknown. In the present study, we examine the role of the transcription factor RUNX2 in the regulation of receptor tyrosine kinase (RTK) expression in melanoma. We have demonstr...

For many years, real-time DGPS and RTK correction data distribution have been providing GPS users a means to accomplish their tasks with high accuracy positioning in real-time. Dial-up systems over phone line or local area network (LAN) enable users to download data from base stations at remote locations. Radio modems provides wireless communication links between a base station and a rover to e...

In our study, we analyzed the combined standard uncertainty of water table slope assessment done using differential global positioning system (DGPS)-based measurements of water table elevation and distances between measurement locations. We compared and discussed uncertainties in water table slope assessments done in various hypothetical environments of lowland floodplains (water table slopes t...

We previously reported that hypotonic stress stimulated transepithelial Na(+) transport via a pathway dependent on protein tyrosine kinase (PTK; Niisato N, Van Driessche W, Liu M, Marunaka Y. J Membr Biol 175: 63-77, 2000). However, it is still unknown what type of PTK mediates this stimulation. In the present study, we investigated the role of receptor tyrosine kinase (RTK) in the hypotonic st...

Acceptable RTK GPS/GNSS performance is heavily dependent on a relativity unobstructed sky-view, where there are at least five satellites with good geometry available, and on the reliability of the wireless data link used for differential corrections. In “tough” GNSS applications where satellite occlusion is common, such as open cast mining, the RTK based technology often fails to deliver the re...