Cardiac neural crest (CNC) plays a requisite role during cardiovascular development and defects in the formation of CNC-derived structures underlie several common forms of human congenital birth defects. Migration of the CNC cells to their destinations as well as expansion and maintenance of these cells are important for the normal development of the cardiac outflow tract and aortic arch arteri...

Preliminary communication There are currently no appropriate methods to find CNC system software defects and eliminate hidden dangers. In order to improve CNC system reliability, the architecture expansion-based fault location method in CNC system software was proposed in this paper. The failure of CNC system software was 619 analysed, the expansion method of CNC system software architecture wa...

The complex of myxomas, spotty skin pigmentation and endocrine overactivity, or Carney complex (CNC), is a familial multiple endocrine neoplasia and lentiginosis syndrome. CNC is inherited in an autosomal dominant manner and is genetically heterogeneous. Its features overlap those of McCune-Albright syndrome and other multiple endocrine neoplasia (MEN) syndromes. Spotty skin pigmentation is the...

This chapter discusses the realization of direct translation of feature-based CAM files into feature-based CNC part program files. The information infrastructure that allows this to happen is STEP-NC, as described by ISO 14649 Parts 10 and 11. Among the many benefits cited for STEP-NC, the elimination of the costly and inefficient process of post-processing using one standard CNC definition is ...

Development of the facial skeleton depends on interactions between intrinsic factors in the skeletal precursors and extrinsic signals in the facial environment. Hox genes have been proposed to act cell-intrinsically in skeletogenic cranial neural crest cells (CNC) for skeletal pattern. However, Hox genes are also expressed in other facial tissues, such as the ectoderm and endoderm, suggesting t...

This paper presents a comprehensive virtual simulation model for CNC systems. The Virtual CNC (VCNC) has a modular architecture, allowing a real CNC to be prototyped quickly from standard library functions for feed drive models, feedback devices, axis control laws, and trajectory interpolation. Additional CNC modules can easily be prototyped and integrated to the VCNC by the user. Various appli...

The desire to develop high-value end-products derived from renewable resources is continuously growing as a result of environmental awareness and the depletion of fossil resources. In this context, nanocelluloses have gained great interest during recent decades owing to their renewability, abundancy and remarkable physical and mechanical properties. The aim of the present work was to investigat...

The aim of the next generation of computer numerically controlled (CNC) machines is to be portable, interoperable and adaptable. Over the years, G-codes (ISO 6983) have been extensively used by the CNC machine tools for part programming and are now considered as a bottleneck for developing next generation of CNC machines. A new standard known as STEP-NC is being developed as the data model for ...

Here we report the production of highly thermal stable and functional cellulose nanocrystals (CNC) and nanofibrils (CNF) by hydrolysis using concentrated organic acids. Due to their low water solubility, these solid organic acids can be easily recovered after hydrolysis reactions through crystallization at a lower or ambient temperature. When dicarboxylic acids were used, the resultant CNC surf...

Carney complex (CNC) is a multiple endocrine neoplasia (MEN) syndrome associated with other, non-endocrine manifestations such as lentigines, cardiac myxomas and schwannomas. Primary pigmented nodular adrenocortical disease (PPNAD), leading to corticotrophin-independent Cushing’s syndrome is the most frequent endocrine lesion in CNC. The complex has been mapped to 2p16 and 17q22-24, although ad...