نتایج جستجو برای: سطح tnf

تعداد نتایج: 204401  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه اصفهان - دانشکده علوم 1389

مولتیپل اسکلروزیس (ms) یک بیماری عصبی با واسطه ایمنی است که در آن از بین رفتن میلین سلولهای عصبی روی می دهد و بیماری فرساینده دستگاه عصبی مرکزی(cns) است. هیچ آنتی ژن هدف مخصوصی که به وسیله سیستم ایمنی بیماران ms مورد حمله قرار گیرد هنوز شناخته نشده است. علت بیماری ms هنوز شناخته شده نیست. عقیده بر این است که این بیماری با فاکتورهای میکروبی، ژنتیکی و یا محیطی ارتباط دارد. مولتیپل اسکلروزیس به عن...

Atieh Mohammadi, Fatemeh Mosaffa, Javad Behravan, Khalil Abnous Melika Ehtesham Gharaee Morteza Ghandadi, Negin Haj-Ali,

Objective(s): Acquisition of TNF-α resistance plays role in the onset and growth of malignant tumors. Previous studies have demonstrated that MCF-7 cell line and its doxorubicin resistant variant MCF-7/Adr are resistant against the cytotoxic effects of TNF-α. In this study, we investigated the role of Akt activation in resistance of MCF-7 and MCF-7/Adr against TNF-α cytotoxicity. Materials and ...

Journal: :گوارش 0
mohammad reza fariborzi fatemeh farahmand gholam hosein fallahi mohammad taghi ashtyani masumeh hashemi azade kiumarsi

background : most diagnostic tests for biliary atresia (ba) are invasive. this study evaluates the sensitivity and specificity of serum  tumor necrosis factor-α (tnf-α) for diagnosing extra hepatic biliary duct atresia (ehba) in infants. materials and methods : infants with cholestasis who were admitted to children′s medical center hospital were evaluated. a total of 50 infants (20 with ehba an...

Journal: :iranian journal of immunology 0
marzieh ebrahimi department of immunology, faculty of medical science, tarbiat modares university zuhair mohammad hassan department of immunology, faculty of medical science, tarbiat modares university jamshid hadjati department of immunology, school of medicine, tehran university of medical sciences parisa hayat cell and molecular research center, iran university of medical sciences , tehran, iran seyed mohammad moazzeni department of immunology, faculty of medical science, tarbiat modares university

background: tumor necrosis factor alpha (tnf-α) is a primary mediator of immune regulation and might be required in the early stages of dc development from cd34+ cells. however, details of optimal timing of exposure to tnf-α in dc development process in monocytes or non-purified hematopoitic cells are still lacking and clear benefits of this approach to the development of dcs remain to be valid...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه گیلان - دانشکده علوم پایه 1393

ناباروری، ناتوانی یک زوج در باردار شدن پس از یک سال رابطه جنسی بدون جلوگیری از بارداری می باشد. اسپرماتوژنز، به شماری از مولکول های سیگنالینگ محلی که ادغام و ارتباط میان انواع مختلف سلولی هنگام تنظیم هورمونی بلوغ سلول های زایا در بیضه را فراهم می کنند، بستگی دارد. کنترل این نظارت محلی توسط تعداد زیادی از سیتوکین ها از جمله فاکتور نکروز دهنده تومور آلفا (tnf?)، پشتیبانی می شود.در بیضه ها، گیرنده...

Journal: :iranian journal of immunology 0
hojjatollah shokri mycology research centre, faculty of veterinary medicine, tehran university farzad asadi department of biochemistry, faculty of veterinary medicine, tehran university ali reza bahonar department of epidemiology, faculty of veterinary medicine, tehran university, tehran, iran ali reza khosravi mycology research centre, faculty of veterinary medicine, tehran university

background: herbal medicines have been used since ancient times for treatment of a range of diseases and have represented stimulatory effects on the function of innate immunity. objective: to evaluate the effects of zataria multiflora (z. multiflora) on the function of innate immunity including phagocytic activity and tnf-α secretion in animal model. methods: eight balb/c mice were divided into...

انوشه, صابر, سیف, شیما, فرنیا, پریسا, مسجدی, محمد رضا, نوروزی, جمیله, ولایتی, علی‌اکبر, کارگر, محمد, کاظم پور, مهدی,

Background and Objective: Tuberculosis (TB) caused by Mycobacterium tuberculosis, is an infectious disease in human which kills nearly three millions of people annually. Approximately, one - third of the world populations are infected with this bacteria and 5 - 10 % of them develop the active form of the disease. Individuals are different in susceptibility to TB infection. These differences mig...

Journal: :iranian journal of basic medical sciences 0
morteza ghandadi department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran atieh mohammadi department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran javad behravan department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran biotechnology research center, mashhad university of medical sciences, mashhad, iran khalil abnous pharmaceutical research center, department of medicinal chemistry, school of pharmacy, mashhad university of medical sciences, mashhad, iran negin haj-ali department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s): acquisition of tnf-α resistance plays role in the onset and growth of malignant tumors. previous studies have demonstrated that mcf-7 cell line and its doxorubicin resistant variant mcf-7/adr are resistant against the cytotoxic effects of tnf-α. in this study, we investigated the role of akt activation in resistance of mcf-7 and mcf-7/adr against tnf-α cytotoxicity. materials and ...

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