couple of hours later, there was swelling and reddening of the margins of the ulcers, frequently accompanied by fever up to 38°C. These symptoms lasted for a few hours and subsided spontaneously or with the help of minor analgesics. The patients tolerated this inconvenience, because they soon saw a favorable response. In fact, the latter was dramatic in three of them (patients no. 1, 2, and 4) ...

IN MYELOMA, THE ROLE of the bone marrow microenvironment has been shown to be of increasing importance in supporting the malignant plasma cell.1,2 Specifically, nonmalignant stromal cells in the bone marrow from myeloma patients have been shown to promote the growth and prevent the apoptosis of malignant plasma cells largely by the production of interleukin-6 (IL-6).1-3 Recently, a new member o...

This paper addresses the NOE path planning with incomplete information. We first define the path planning for NOE flight. Then we discuss how to divide the problem into several subproblems. For each of the subproblems, we propose a clear definition along with a brief description of the solutions to the subproblem.

The ATP-binding cassette (ABC) family of transporters, including ABCC3, is a large family of efflux pumps that plays a pivotal role in the elimination of xenobiotics from the body. ABCC3 has been reported to be induced during hepatic stress conditions and through the progression of some forms of cancer. Several lines of evidence have implicated the transcription factor nuclear factor (erythroid...

In an era of high-profile hacks, information leaks and cybercrime, cybersecurity is the focus of much corporate and state-funded research. Data visualization is regarded as an important tool in the detection and prediction of risk and vulnerability in cybersecurity, but discussion tends to remain at the level of the usability of visualization tools and how to reduce the cognitive load on the co...