This study describes the membrane transport mechanisms used by lobster (Homarus americanus) hepatopancreatic epithelial lysosomes to accumulate and sequester heavy metals from the cytosol, and thereby aid in the regulation of these ions entering the animal from dietary constituents. The present investigation extends previous work describing lysosomal metal uptake by cation exchange with protons...

Amaç: Bu çalışma 2015-2019 yılları arasında sonbahar ve kış aylarında Adana (Ceyhan, Çukurova, Karaisalı, Sarıçam, Seyhan, Yumurtalık Yüreğir ilçeleri ile Yakapınar mahallesi) Mersin (Tarsus ilçesi Yenice illerinde yaygın olarak marul yetiştiriciliğinin yapıldığı alanlarda mozaik virüsü (Lettuce mosaic virus, LMV)’nün saptanması karakterizasyonu amacıyla yürütülmüştür.Yöntem Bulgular: Arazi çık...

PURPOSE To investigate the coronary venous system and its relation to adjacent structures using 256-slice computed tomography (CT). MATERIALS AND METHODS The study consisted of 102 patients who underwent coronary CT angiography (CTA) using 256-slice CT. For each patient, the coronary venous system and its relation to adjacent structures were evaluated. The appropriate locations and diameters ...

Acute hepatitis B (AHB) is a self-limiting condition in more than 95% of cases. Treatment is however recommended in patients with severe AHB (<1% of cases), aiming to prevent liver failure and death. Various nucleos(t)ide analogues (NA) have been found to be effective in severe AHB, although NA-resistant strains causing AHB have been also recently reported. The use of tenofovir in severe AHB ha...

BACKGROUND Long-term treatment of chronic hepatitis B (CHB) with nucleos(t)ide analogs results in the emergence of drug-resistant hepatitis B virus (HBV) harboring mutations in the polymerase (P) gene. The Phyllanthus extract has anti-HBV activity; however, its antiviral activity against lamivudine (LMV)-resistant mutants has not been examined. METHODS HBV harboring LMV-resistant mutations (r...

Several viruses have been reported to infect lettuce. The most important is Lettuce mosaic virus (LMV), a potyvirus found worldwide transmitted by seeds and aphids, in a non-persistent manner. LMV causes quite variable symptoms, including mosaic, dwarfing, failure to form proper heads, and sometimes necrotic reactions. Cultivars carrying the mo11 and mo12 genes have resistance to the common str...

Objective: This study was designed to prospectively evaluate the antiviral responses and evolution of resistance mutations during adefovir (ADV) plus lamivudine (LMV) therapy in patients with entecavir (ETV)-resistant hepatitis B virus (HBV) infection. Methods: Twenty chronic hepatitis B (CHB) patients who had been receiving ETV for more than 6 months and developed virologic breakthrough due to...