Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant proliferative disorder that may progress to multiple myeloma, a malignant plasma cell neoplasia. We evaluated differential scanning calorimetry (DSC) as an experimental tool for differentiating serum samples of MGUS patients from healthy individuals. DSC thermograms can be used for monitoring changes in the serum proteo...

William Harvey Research Limited is the trading entity of the William Harvey Research Foundation a registered charity. Registered in England reg. no. 2437946. Chief Executive: Professor B.J.R. Whittle PhD, DSc Directors: Professor N. Benjamin FRCP DM, Dr J.A. Davies, Professor R.J. Flower DSc, Professor C. Thiemermann MD PhD and Professor D.A. Willoughby DSc FRCPath. WILLIAM HARVEY RESEARCH CONF...

Dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) is used to track the first pass of an exogenous, paramagnetic, nondiffusible contrast agent through brain tissue, and has emerged as a powerful tool in the characterization of brain tumor hemodynamics. DSC-MRI parameters can be helpful in many aspects, including tumor grading, prediction of treatment response, likelihood of ma...

BACKGROUND Decidua is in close contact with the fetal trophoblasts, and involved in immune relationship of mother to fetus. However, the roles of decidua and decidual stromal cells (DSC) in materno-fetal immune regulation remain to be elucidated. In the present study, the expression and regulation of chemokines and their receptors in decidua and DSCs were investigated. METHODS AND RESULTS The...

Differential Scanning Calorimetry (DSC) is used to measure heat flow into or out of a sample as it is exposed to a controlled thermal profile. DSC provides both qualitative and quantitative information about material transitions such as the glass transition, crystallization, curing, melting, and decomposition. For some of these transitions, DSC can provide not only the temperature at which the ...

This paper presents an artificial-neural-network-based direct-self-control (ANN–DSC) scheme for an inverter-fed three-phase induction motor. In order to cope with the complex calculations required in direct self control (DSC), the proposed artificial-neural-network (ANN) system employs the individual training strategy with fixed-weight and supervised models. A computer simulation program is dev...

During visual fixation, the image of an object is maintained within the fovea. Previous studies have shown that such maintenance involves the deep superior colliculus (dSC). However, the mechanisms by which the dSC supports visual fixation remain controversial. According to one view, activity in the rostral dSC maintains gaze direction by preventing neurons in the caudal dSC from issuing saccad...

BACKGROUND AND PURPOSE The purpose of this study was to evaluate the potential clinical value of arterial spin-labeled (ASL) perfusion MRI in acute ischemic stroke (AIS) through comparison with dynamic susceptibility contrast (DSC) enhanced perfusion MRI. METHODS Pseudocontinuous ASL with 3-dimensional background-suppressed gradient and spin echo readout was applied with DSC perfusion MRI on ...