Recent studies have shown a role for miRNAs in aging and age-related diseases, and the modulation of miRNA expression by diet attracts attention as a new therapeutic strategy. Here, we focused on identifying specific exosomal miRNAs derived from serum of aged rats and the effect of short-term calorie restriction (CR) on their expression. Exosomes from serum of young (7-month), old (22-month), a...

Abstract Introduction Mondor's Disease (MD) is a rare condition characterised by thrombophlebitis of the superficial veins breast and anterior chest wall. Cases associated with inflammatory bowel disease are rare. Case A 54-year-old male presented to symptomatic clinic 6-week history painful linear area on anterolateral aspect his left There was no trauma or underlying coagulopathy. He also des...

Here we report the synthesis of storable N-phenylcarbamate palladacycles that showed robust reactivity in the cross-coupling reaction with an alkyne-encoded protein with a second-order rate constant approaching 19 770 ± 930 M(-1) s(-1).

This paper presents new experimental findings on the hot-carrier-induced degradation in lateral DMOS with different gate oxide thickness and when it is stressed at elevated temperature. For thin oxide devices, the generation of interface states and the trapped holes are the causes of the reduction of IDS in the linear region and the increase of IDSAT in the saturation region, respectively. For ...

The pionic width of the !(782) meson within a well-deened, unitary quantum eld theory of (anti-)particles and (anti-)holes Abstract We investigate the indirect generation of the partial width of the !(782) meson with respect to the reaction !(782) ! (770) ! + ? 0 within the context of a \Unitary Effective Resonance Model" (UERM), which has previously been applied to resonant fermionic eld opera...

Squirrel monkeys (Saimiri sciureus) inoculated intratracheally with 10(4.2)-10(8.2) egg median infectious doses (EID50) of type A influenza virus (H3N2) responded with clinical illness including such signs as fever, sneezing or coughing, coryza, and increased respiratory rates. Necropsy studies performed six days after inoculation revealed bronchopneumonia in addition to a mild tracheitis. Squi...

1 International Emergency and Refugee Health Branch, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America. Send correspondence and reprint requests to: Benjamin A. Sklaver, International Emergency and Refugee Health Branch, National Center for Environmental Health, Centers for Disease Control and Prevention, 1600 Clifto...