The murine suppressive factor of allergy (SFA) has been purified from a T-cell hybridoma and found to consist of two functionally and biochemically distinct protein molecules. One protein (17 kDa) modulates the low-affinity Fc receptor for IgE on lymphocytes (i.e., CD23); it decreases the binding avidity of IgE to CD23-bearing B cells without affecting quantitative expression of CD23 and is thu...

ments suggest that at physiological concentrations, only urate contributes to the artifactually high pre-dialysis values. When a standard serum sample was increased in concentration (in vitro) from 11.6 to 54 mmol/L in urea, from 97 to 1130 mmol/L in creatinine, and from 0.31 to 1.38 mmol/L in urate, values for apparent SFA were unaffected by urea or creatinine changes, but rose 13% in the pres...

Slow Feature Analysis (SFA) extracts features representing the underlying causes of changes within a temporally coherent high-dimensional raw sensory input signal. Our novel incremental version of SFA (IncSFA) combines incremental Principal Components Analysis and Minor Components Analysis. Unlike standard batch-based SFA, IncSFA adapts along with non-stationary environments, is amenable to epi...

BACKGROUND The apolipoprotein E (APOE) gene promoter polymorphism (-219G-->T) has been associated with increased risk of myocardial infarction, premature coronary artery disease, and decreased plasma apolipoprotein E concentrations. OBJECTIVE We aimed to determine in healthy subjects whether this polymorphism modifies the susceptibility of LDL to oxidation and the lipid response to the conten...

Background: The apolipoprotein E (APOE) gene promoter polymorphism ( 219G3T) has been associated with increased risk of myocardial infarction, premature coronary artery disease, and decreased plasma apolipoprotein E concentrations. Objective: We aimed to determine in healthy subjects whether this polymorphism modifies the susceptibility of LDL to oxidation and the lipid response to the content ...

The lamellar phase of a lyotropic solution in a confined geometry is investigated with a surface force apparatus (SFA). The measured interaction between the two SFA surfaces immersed in the mesophase is periodic, oscillatory, decaying, and discontinuous. A model is developed to account for the specific confining geometry of the SFA It is based on an array of concentric dislocation loops that al...

Abstract—The ubiquity of multicore architectures in modern computing devices requires the adaptation of algorithms to utilize parallel resources. String pattern matching based on finite automata (FAs) is a method that has gained widespread use across many areas in computer science. However, the structural properties of the pattern matching algorithm have hampered its parallelization. To overcom...

Saturated fatty acid (SFA)-related lipotoxicity is a pathogenesis of diabetes-related renal proximal tubular epithelial cell (PTEC) damage, closely associated with a progressive decline in renal function. This study was designed to identify a free fatty acid (FFA) metabolism-related enzyme that can protect PTECs from SFA-related lipotoxicity. Among several enzymes involved in FFA metabolism, we...