Developmental cortical malformations are common in patients with intractable epilepsy; however, mechanisms contributing to this epileptogenesis are currently poorly understood. We previously characterized hyperexcitability in a rat model that mimics the histopathology of human 4-layered microgyria. Here we examined inhibitory and excitatory postsynaptic currents in this model to identify functi...

Distributed computing has been considered for decades as a promising way of speeding up software execution, resulting in a valuable collection of safe and efficient concurrent algorithms. With the pervasion of multi-core processors, parallelization has moved to the center of attention with new challenges, especially regarding scalability to tens or even hundreds of parallel cores. In this paper...

Diabetes is a significant and growing concern, with over 246 million people around the world living with the disease and another 308 million with impaired glucose tolerance. Depending on the resources of different nations, intervention has generally focused on optimizing overall glycaemic control as assessed by glycated haemoglobin (HbA(1c)) and fasting plasma glucose (FPG) values. Nevertheless...

superconducting materials are capable of trapping extremely high magnetic fields. this property and meissner effect of superconductors causes a levitation force between bulk superconductors and a permanent magnet (pm). this levitation force has possible industrial applications such as permanent magnet guideways (pmg). because of the high price of permanent magnets, the optimization of pmg desig...

BACKGROUND AND PURPOSE During the review of MR studies of multiple patients with polymicrogyria (PMG), it was noted that the patterns of cortical abnormality differed significantly among affected patients. In particular, the cortex appeared very thin in some patients, but was thick in others. The purpose of the present study was to attempt to clarify the cause of the different imaging appearanc...

Myocardial ischemia is characterized by a decrease in phosphocreatine (PCr) and Mg(2+)-ATP contents as well as an accumulation of myosin ATPase reaction products (inorganic phosphate [P(i)], protons, and Mg(2+)-ADP). The possibility that these metabolites play a role in rigor tension development was checked in rat ventricular Triton X-100-skinned fibers. Rigor tension was induced by stepwise de...

This study proposed a cost effective method of wind energy conversion system (WECS) incorporating permanent magnet generator (PMG) and single stage power converter. Axial flux PMG can generate rated voltage and frequency even at a lower speed and hence more suitable for direct drive WECS. To get desired voltage and frequency in continuously varying wind conditions, a new type of WECS with singl...