We report here that the rat heart is a site of oxytocin (OT) synthesis and release. Oxytocin was detected in all four chambers of the heart. The highest OT concentration was in the right atrium (2128 +/- 114 pg/mg protein), which was 19-fold higher than in rat uterus but 3.3-fold lower than in the hypothalamus. OT concentrations were significantly greater in the right and left atria than in the...

objective(s): the effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study.   materials and methods: male wistar rats were randomly divided into control sedentary (c), moderate trained (mt), (v=20 m/min, 30 min/day for 6 days a week, 8 weeks), overtrained (ot) (v=25 m/min, 60min/day for 6 days a week, 11 weeks) and recovered overtrained (or)...

We have shown previously that an intravenous injection of oxytocin (OT) in ovariectomized (OVX) rats initiates a circadian rhythm of prolactin (PRL) secretion similar to that observed after cervical stimulation (CS). In this study, we investigated the pathway through which OT triggers the PRL rhythm. We first tested whether an intracerebroventricular injection of OT could trigger the PRL secret...

BACKGROUND & OBJECTIVES Oxytocin (OT) injections to milch cattle for milk letdown have become a common practice amongst dairy farmers in India. Although there is no reported evidence, it is widely presumed that long term consumption of such milk leads to adverse health consequences. However, there is no information on the effect of exogenous OT injections on milk OT content and its stability du...

Skill learning and instrumental conditioning have a long association with the behaviorist research program and are often thought of in terms of rote learning of simple stimulus–response (S–R) associations based on external rewards. These forms of learning have also been strongly associated with the striatum of the basal ganglia, with different striatal regions apparently making various differen...

Since the early 1990s, Optimality Theory (OT) has quickly gained ground in phonology. Its main appeal lies in two characteristics: the focus on wellformedness of the output and the softness of constraints, where a constraint can be violated in order to satisfy more important requirements. A conspicuous characteristic of classic OT is that all constraints on the output should compete with each o...

Despite the accumulating evidence suggesting that the neuropeptide oxytocin (OT) plays a role in neuropsychiatric disorders characterized by social dysfunction, the influence of OT on the nonsocial aspects of learning and memory have been less investigated. To foster research in this area, we review the effects of OT on learning and memory in animal models and humans. In healthy animal models, ...

We investigated the production of oxytocin (OT) and oxytocin-neurophysin (bNpI) by bovine granulosa cells cultured in presence of 10% foetal calf serum, a condition known to induce spontaneous luteinization of these cells. The production of immunoreactive OT was significantly higher in the cultures of granulosa cells harvested from large follicles than in those derived from small follicles. Chr...