نتایج جستجو برای: اکسیم oxime

تعداد نتایج: 2718  

Journal: :AJNR. American journal of neuroradiology 1996
J Patterson D J Wyper D M Hadley

ژورنال: :مجله علوم پزشکی رازی 0
مهدی بلالی m. balali

سموم فسفردار آلی به میزان وسیعی در دفع آفات نباتی وهم به عنوان عوامل اعصاب در جنگهای شیمیایی مورد استعمال قرار گرفته اند. حشره کش های فسفردار بطور فراوان وارد کشور شده و متاسفانه اغلب بدون کنترل در دسترس افراد قرار می گیرند. بهمین دلیل مسمومیت حاد با این سموم بویژه نوع عمدی بسیار شایع بوده به نحوی که 250 نفر ( 8/21%)از مسمومین بستری بیمارستان امام رضا(ع) مشهد را در سال 1373 شامل گردیده است. سمو...

Journal: :European journal of medicinal chemistry 2012
Arzu Karakurt Mehmet A Alagöz Burcu Sayoğlu Unsal Calış Sevim Dalkara

Twenty-three new oxime ester derivatives of nafimidone were synthesized with the prospect of potential anticonvulsant activities. MES and ScM tests were employed for their anticonvulsant activities and rotorod test for neurological deficits. Eighteen compounds were found to be protective against MES seizures. Alkyl (1-8) and arylalkyl (9, 10) oxime ester derivatives were found to be more active...

Journal: :Journal of Photopolymer Science and Technology 2021

Four N-phenyl substituted carbazole oxime ester photoinitiators were synthesized and their structure-activity relationship systematically investigated. These have a broad absorption in the range of 300-400 nm tail extends above 400 nm. Under 405 LED light irradiation, esters undergo photodecarboxylation generate active free radicals to induce polymerization acrylates. The tert-butyl aldehyde-ox...

Journal: :Angewandte Chemie 2021

Vicinal aminoalcohols are widespread structural motifs in bioactive molecules. We report the development of a new dioxazolone reagent containing p-nitrophenyldifluoromethyl group, which 1. displays good safety profile; 2. shows remarkably high reactivity oxime-directed iridium(III)-catalyzed amidation unactivated C(sp3)−H bonds; 3. leads to amide products can be hydrolyzed under mild conditions...

Journal: :Toxicology mechanisms and methods 2009
John A Guarisco John C O'Donnell Jacob W Skovira John H McDonough Tsung-Ming Shih

Organophosphorus compounds (OPs) are potent inhibitors of acetylcholinesterase (AChE). Treatment for OP poisoning is by administration of atropine sulfate, an oxime, and diazepam. Oximes such as 2-PAM are used to reactivate OP-inhibited AChE so as to restore normal enzymatic function and serve as a true antidote. There are reports of non-enzymatic hydrolysis by oximes of acetylthiocholine in in...

Journal: :Plant physiology 2011
Kirsten Jørgensen Anne Vinther Morant Marc Morant Niels Bjerg Jensen Carl Erik Olsen Rubini Kannangara Mohammed Saddik Motawia Birger Lindberg Møller Søren Bak

Cassava (Manihot esculenta) is a eudicotyledonous plant that produces the valine- and isoleucine-derived cyanogenic glucosides linamarin and lotaustralin with the corresponding oximes and cyanohydrins as key intermediates. CYP79 enzymes catalyzing amino acid-to-oxime conversion in cyanogenic glucoside biosynthesis are known from several plants including cassava. The enzyme system converting oxi...

Journal: :The Biochemical journal 2013
Zoran Radić Trevor Dale Zrinka Kovarik Suzana Berend Edzna Garcia Limin Zhang Gabriel Amitai Carol Green Božica Radić Brendan M Duggan Dariush Ajami Julius Rebek Palmer Taylor

In the present paper we show a comprehensive in vitro, ex vivo and in vivo study on hydrolytic detoxification of nerve agent and pesticide OPs (organophosphates) catalysed by purified hBChE (human butyrylcholinesterase) in combination with novel non-pyridinium oxime reactivators. We identified TAB2OH (2-trimethylammonio-6-hydroxybenzaldehyde oxime) as an efficient reactivator of OP-hBChE conjug...

Journal: :Bioinorganic Chemistry and Applications 2003
Edgars Abele Ramona Abele Pavel Arsenyan Irina Shestakova Iveta Kanepe Inga Antonenko Juris Popelis Edmunds Lukevics

Silicon and germanium containing pyridine aldoxime, ketoxime and amidoxime O-ethers have been prepared using phase transfer catalytic systems oxime alkyl halide solid KOH 18-crown-6 benzene and oxime alkyl halide solid K(2)CO(3) or Cs(2)CO(3) 18-crown-6 toluene. Cytotoxic activity of silicon and germanium containing pyridine oxime O-ethers was tested in vitro on two monolayer tumor cell lines: ...

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