The function of occludin (Occ) in the tight junction is undefined. To gain insight into its role in epithelial cell biology, occludin levels in Madin-Darby canine kidney II cells were suppressed by stably expressing short interfering RNA. Suppression of occludin was associated with a decrease in claudins-1 and -7 and an increase in claudins-3 and -4. Claudin-2 levels were unaffected. The tight ...

Distributed storage systems run transactions across machines to ensure serializability. Traditional protocols for distributed transactions are based on two-phase locking (2PL) or optimistic concurrency control (OCC). 2PL serializes transactions as soon as they conflict and OCC resorts to aborts, leaving many opportunities for concurrency on the table. This paper presents ROCOCO, a novel concurr...

Occludin is the first identified protein in the tight junction (TJ), but its function has remained for the most part obscure. TJs have been demonstrated to play important roles in the inner ear function, and occludin is expressed in all the epithelial TJs in the inner ear. Thus, we examined the inner ears of occludin-deficient (Occ(-/-)) mice. Although inner ears initially developed normally in...

The Optimistic Concurrency Control (OCC) method has been commonly used for in-memory databases to ensure transaction serializability — a transaction will be aborted if its read set has been changed during execution. This simple criterion to abort transactions causes a large proportion of false positives, leading to excessive transaction aborts. Transactions aborted false-positively (i.e. false ...

The results of this study indicate that the latency and silent periods of OCC cycles do not vary among groups representing distinct dentitional stages. The mean latency period durations obtained from the OCC cycles of the subjects in this study ranged from 16.6 to 19.5 msec and demonstrated the smallest SD of all parameters measured. The mean silent period durations ranged from 11.6 to 15.4 mse...

Mammals ovulate an oocyte cumulus complex (OCC), which contains, in addition to the oocyte, numerous cumulus cells and an extensive extracellular matrix (Mahi-Brown and Yanagimachi, 1983; Talbot and DiCarlantonio, 1984). OCCs are ovulated into the peritoneal or bursal cavity and then picked up by the infundibulum of the oviduct and carried into the ampulla where fertilization occurs (Harper, 19...

Although an optimistic approach has been shown to be better suited than locking protocols for real-time database systems (RTDBS), it has the problems of unnecessary restarts and heavy restart overhead. In this paper we identify the unnecessary restart problem in OCC-TI (Optimistic Concurrency Control with Time Intervals), propose a solution to this problem and demonstrate that the solution will...