Neuromodulators, including transmitters and peptides, modify neuronal excitability. In most neurons, multiple neuromodulator receptors are present on a single cell. Previous work has demonstrated either occlusive or additive effects when two neuromodulators that target the same ion channel are applied together. In this study, we characterize the modulation of Ca2+ and K+ channels in embryonic c...

In this paper, an important application of Self-Organizing Maps (SOM) to construction of adaptive meshes is considered. It is shown that application of the basic SOM model leads to a number of problems like inaccurate fitting the border of a physical domain, mesh self-crossings, etc. The composite SOM model is proposed which is based on the composition of a number of SOM models interacting in a...

The Self-Organizing Map (SOM) is a useful and strong tool for data analysis, especially for large data sets or data sets of high dimensionality. SOM visualizations map the data model dimensions to visual dimensions like color and position, thus they help exploring the SOM. Visualization can also involve the data itself so that it helps accessing information that are not available in the trained...

Exact estimates of soil clay (<2 μm) and silt (2-20 μm) contents are crucial as these size fractions impact key soil functions, and as pedotransfer concepts based on clay and silt contents are becoming increasingly abundant. We examined the effect of removing soil organic matter (SOM) by H2O2 before soil dispersion and determination of clay and silt. Soil samples with gradients in SOM were retr...

Abstract. In the article, an additional visualization of self-organizing maps (SOM) has been investigated. The main objective of self-organizing maps is data clustering and their graphical presentation. Opportunities of SOM visualization in four systems (NeNet, SOM-Toolbox, Databionic ESOM and Viscovery SOMine) have been investigated. Each system has its additional tools for visualizing SOM. A ...

The distribution and morphology of neurons containing somatostatin (SOM) was investigated in the amygdala (CA) of the pig. The SOM-immunoreactive (SOM-IR) cell bodies and fibres were present in all subdivisions of the porcine CA, however, their number and density varied depending on the nucleus studied. The highest density of SOM-positive somata was observed in the layer III of the cortical nuc...

Understanding the role of soil organic matter (SOM) in soil quality and subsequent crop yield and input requirements is useful for agricultural sustainability. SOM is widely considered to affect a wide range of soil properties, however, great uncertainty still remains in identifying the relationships between SOM and crop yield due to the difficulty in separating the effect of SOM from other yie...

A previous study showed that SOMNUS (SOM), which encodes a C3H-type zinc finger protein, is a key negative regulator of seed germination that acts downstream of PHYTOCHROME INTERACTING FACTOR3-LIKE5 (PIL5). However, it was not determined if PIL5 is the sole regulator of SOM expression. Public microarray data suggest that the expression of SOM mRNA is regulated also by ABSCISIC ACID INSENSITIVE3...

Somatostatin (SOM) is a widely distributed peptide in the central nervous system and exerts a variety of hormonal and neural actions. Although SOM is assumed to play an important role in spinal nociceptive processing, its exact function remains unclear. In fact, earlier pharmacological studies have provided results that support either a facilitatory or inhibitory role for SOM in nociception. In...

In this paper, two generalizations of the SOM are introduced. The first of these extends the SOM to deal with more generalized classes of objects besides the vector dataset. This generalization is realized by employing modular networks instead of reference vector units and is thus called a modular network SOM (mnSOM). The second generalization involves the extension of the SOM from ‘map’ to ‘ho...