Cholesterol and sex steroid hormones including androgens and estrogens play a critical role in the development and progression of urological diseases such as prostate cancer. This disease remains the most commonly diagnosed malignant tumor in men and is the leading cause of death from different cancers. Attempts to understand the role of cholesterol and steroid metabolism in urological diseases...

Telomere maintenance is essential to ensure proper size and function of organs with a high turnover. In particular, a dwarf phenotype as well as phenotypes associated to premature loss of tissue regeneration, including the skin (hair loss, hair graying, decreased wound healing), are found in mice deficient for telomerase, the enzyme responsible for maintaining telomere length. Coincidental with...

چکیده:بازی تاج و تخت نخستین کتاب از مجموعه نغمه‌ی یخ آتش، اثر نویسنده آمریکایی جورج ریموند ریچارد مارتین، داستانی خیالی-حماسی است که در قلمرو "وسترس" رخ می دهد. جریان اصلی داستان، حول محور کشمکش جنگ برای تسلط به سلطنت این راستا داستان‌های دیگری درون آن متولد شوند. آنچه پیرنگ داستان را متمایز می‌کند، وجود آشوب هرج مرج درنظام حکمرانی دنبال رهبری یکپارچه بر جهان بی‌نظم می‌باشد. تحقیق با تمرکز اصول...

Paediatric bilateral multiple trigger fingers are extremely rare. The underlying etiopathogenesis and hence the surgical principles of management of trigger finger in children are different from those of pediatric trigger thumb and adult trigger finger. In this paper, we report the case of a 5 year old girl with congenital trigger digits involving the middle, ring and little fingers of both han...

در این مقاله، به بررسی اثر پارامترهای کاری گوناگون بر شکل تپ‌های خروجی یک لیزر 2CO تپی فشار اتمسفری پرتکرار دست‌ساز (با آهنگ تکرار تا kHz 1) پرداخته شده است. راستا، عوامل گوناگونی هم­چون: نسبت گاز 2N، He و بازتابندگی آینه جلویی تغییر داده شدند انرژی گسیلی هر از حالت‌ها ثبت مشخصه‌یابی شدند. نشان شد که با گازهای 2N He، می‌توان دیرش زمانی میخه دنباله‌ی تپ‌ها را بازه‌ی ns 140-95 µs 5/3-5/1 تنظیم نم...

cartilage hair hypoplasia (chh), is a rare cause of metaphyseal chondrodysplasia and short stature. other features included hair abnormality, immunodeficiency, anemia, gastrointestinal disorders (hirschsprung disease, celiac, …) and increased risk of cancer. the disease is an autosomal recessive disorder and previously has not been reported in iran. we report a 9-year-old boy diagnosed as carti...

kawasaki disease is a multi system disorder with varying clinical expressions. this disease is an acute systemic vasculitis of unknown etiology that has recently recognized as a leading cause of acquired heart disease in children of many developed countries. we describe an unusual instance of hair loss in a patient with kawasaki disease. a 26 months old boy developed prolonged high fever, bilat...

manganese and cobalt concentrations in hair and nail were determined by flame atomic absorption spectrophotometer (aas).the mean manganese in hair and nail were 0.54 â± 0.35mg/g and 0.68 â± 0.30mg/g while the mean cobalt in hair and nail were 0.30 â± 0.24mg/g and 0.460.37mg/g respectively. a progressive increase in cobalt concentrations in hair and nails with age indicated no significant differ...