BACKGROUND It has been hypothesised that vitamin D receptor (VDR) gene polymorphisms may influence both the risk of cancer occurrence and prognosis. MATERIALS AND METHODS The distribution of VDR Taq I polymorphism in 64 patients with OSCC was determined by polymerase chain reaction based restriction fragment length polymorphism (RFLP) and compared with that of 87 healthy controls. RESULTS T...

We extend Dechow and Dichev’s [2002] model of current accruals quality (CAQ) to consider total accruals quality (TAQ). While the two measures are conceptually similar (both reflect the standard deviation of the residuals from the mapping of accruals into lead and lag cash flows), they differ in terms of the definitions of accruals and cash flows as well as the number of lead and lag cash flow t...

Thermus aquaticus (Taq) DNA polymerase was used to measure the extension efficiency for all configurations of matched and mismatched base pairs at template-primer 3'-termini. The transition mispairs, A(primer).C, C.A, G.T, and T.G were extended 10(-3) to 10(-4)-fold less efficiently than their correctly paired counterparts. Relative efficiencies for extending transversion mispairs were 10(-4) t...

BACKGROUND The aim of the study was to determine the influence of DRD2 gene polymorphisms in exon 8 G/A (rs 6276) in the promoter region -141 C Ins/Del (rs1799732) and the influence of ANKK-1 gene Taq-1A polymorphism (rs 1800497) on the preference of increasing sucrose concentrations in men with alcohol dependence. SUBJECTS AND METHODS 63 male patients with alcohol dependence were genotyped f...

2.Cusi, M.G., M. Valassina and P.E. Valensin. 1994. Comparison of M-MLV reverse transcriptase and Tth polymerase activity in RTPCR of samples with low virus burden. BioTechniques 17:1034-1036. 3.Fiorenza, M.T. and F. Mangia. 1998. Quantitative RT-PCR amplification of RNA in single mouse oocytes and preimplantation embryos. BioTechniques 24:618-623. 4.Huang, Z., M.J. Fasco and L.S. Kaminsky. 199...

We demonstrate that despite lacking a 3'----5' proofreading exonuclease, the Thermus aquaticus (Taq) DNA polymerase can catalyze highly accurate DNA synthesis in vitro. Under defined reaction conditions, the error rate per nucleotide polymerized at 70 degrees C can be as low as 10(-5) for base substitution errors and 10(-6) for frameshift errors. The frequency of mutations produced during a sin...

This study examines various measures of trading costs estimated from highfrequency (TAQ) data and the extent to which these measures can be estimated from daily data (CRSP). The high-frequency measures tend to be positively correlated. Posted spreads and effective costs are very highly correlated. Price impact measures and other statistics derived from dynamic models, however, are only modestly...

A novel strategy for heat-mediated activation of recombinant Taq DNA polymerase is described. A serum albumin binding protein tag is used to affinity-immobilize an E. coli-expressed Taq DNA polymerase fusion protein onto a solid support coated with human serum albumin (HSA). Analysis of heat-mediated elution showed that elevated temperatures (> 70 degrees C) were required to significantly relea...