نتایج جستجو برای: آنتاگونیست vegf
تعداد نتایج: 27412 فیلتر نتایج به سال:
زمینه و هدف: فاکتورهای رشد اندوتلیال عروقی ترشح شده از تومور با اتصال به رسپتورهای خود در سطح سلولهای اندوتلیال نقش مهمی در نفوذ پذیری عروقی و رگزایی تومور ایفا می کنند. در این مطالعه پپتید آنتاگونیست فاکتور رشد اندوتلیال عروقی (VEGF) طراحی شد با این هدف که پپتید مورد نظر (VGB4) با تداخل دراتصال فاکتور رشد اندوتلیال عروق به رسپتورهای خود، مسیرهای پیام رسانی در پایین دست را غیر فعال کرده و در ...
مقدمه: لیکن پلان یک بیماری اتوایمیون مزمن التهابی با اتیولوژی نامشخص می باشد. آنژیوژنزیز فرایندی است که منجر به تشکیل عروق خونی جدید از ساختمانهای عروقی از قبل موجود می شود. نقش آنژیوژنزیز، در یک سری از حالات فیزیولوژیک یا پاتولوژیک حفره دهان شامل بیماریهای التهابی مزمن، ترمیم بافتی، تومور و متاستاز بسیار با اهمیت می باشد. هدف: هدف از مطالعه حاضر بررسی فعالیت آنژیوژنتیک در ضایعات رتیکولار، ارو...
statement of problem: recurrent aphthous stomatitis (ras) is one of the most common inflammatory diseases encountered in dental practice, but the precise etiology and pathogenesis of the disease is not fully understood. vascular endothelial growth factor (vegf) is a multifunctional angiogenic cytokine involved in angiogenesis and wound healing. there is evidence that vegf could play an importan...
background: vascular endothelial growth factor (vegf) is a signal protein produced by cells that stimulates angiogenesis and increased vascular permeability. the prognostic value of vegf expression in colorectal cancer is unclear as shown by the discordant results still reported in the literature. this study was designed for the evaluation of vegf expression and correlation with clinicopatholog...
background: stimulation of collateral artery growth (arteriogenesis) and/or capillary network growth (angiogenesis) would be beneficial to the patients with myocardial infarction. to understand the central role of vascular endothelial growth factor (vegf) in biological angiogenesis, we performed molecular analysis of the vegf gene in patients afflicted with acute myocardial infarction (ami). ...
Background: Exercise is considered as the important treatment in diabetic patients and the process of angiogenesis in diabetes can be affected by exercise. The purpose was to investigate the effect of 6 weeks of endurance training in the form of treadmill running on VEGF levels in cardiac muscle of diabetic rats. Materials and Methods: 24 male Wistar rats weighing 245±9.4 g and 8 weeks old wer...
Background & objectives: Osteoarthritis as a result of the destruction of articular cartilage, leads to joint pain and stiffness. The purpose of this study was to investigate the effect of endurance and ozone therapy on the expression levels of FLS and VEGF genes in the knee tissue of rats with knee osteoarthritis. Methods: Subjects were male Wistar rats that were randomly divided into 5 groups...
Background and Objective: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, in which cortical and hippocampus neurons death is the main target of neurodegeneration. In addition to extracellular beta amyloid accumulation and the production of neural tangles, one of effective factors in the pathology of Alzheimer's disease is vascular injury in the elderly including disturbanc...
Background: According to the possible role of Vascular Endothelial Growth Factor (VEGF) in the incidence of oral lichen planus lesions, it seems necessary to evaluate it in patients with Oral Lichen Planus (OLP). Objective: The present study aims to investigate the level of VEGF in patients with OLP. Methods: In this systematic review and meta-analysis study, the search was conducted in online...
Vascular Endothelial Growth Factor (VEGF) plays an important role in tumor angiogenesis. Although several studies revealed on association of VEGF polymorphisms with gastric cancer, still the results are inconclusive.
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