نتایج جستجو برای: δ9
تعداد نتایج: 792 فیلتر نتایج به سال:
Objectives: A liquid/liquid extraction technique on solid support of Δ9-tetradydrocannabinol (THC), 11-hydroxy-Δ9-tetradydrocannabinol (11-OH-THC) and 11-nor-Δ9-tetradydrocannabinol-9-carboxylic acid (THCCOOH) in plasma was developed in order to be assayed by high-performance liquid chromatography and tandem mass spectrometry (HPLC-MS/MS). Methods: The samples were extracted by liquid/liquid ex...
Background As the point of physiology, memories form changes in the conducting message in the neural webs. These changes cause the formation of long-term potentiation. Δ9-THC is a psychotropic component of Cannabis sativa plant. Studies show this matter can bind Cannabinoid receptor in CA1 area of Hippocamp. Thus the aim of this study is to evaluate the effect of aqua extraction Cannabis sativa...
Abbreviations: ECBS, Endocannabinoids; AEA, An amide hydrolase; CB1, Cannabinoid type 1 receptor; CB2 TRPV1, Transient potential vanilloid type 1 receptor; CBD, tex; MPFC, Medial prefrontal córtex; PL, Prelimbic; HI Hippocampus; PAG, Periaqueductal gray matter; THC, Δ9 Elevated plusmaze; VCT, Vogel conflict test; AP, Anteropos ⁎ Corresponding author at: Pharmacology Departme Preto, University o...
Animal studies and preliminary clinical trials have shown that cannabidiol (CBD)-enriched extracts may have beneficial effects for children with treatment-resistant epilepsy. However, these compounds are not yet registered as medicines by regulatory agencies. We describe the cases of two children with treatment-resistant epilepsy (Case A with left frontal dysplasia and Case B with Dravet Syndro...
The non-essential fatty acids, C18:1n9, C16:0, C16:1n7, C18:0 and C18:1n7 account for over 75% of fatty acids in white adipose (WAT) triacylglycerol (TAG). The relative composition of these fatty acids (FA) is influenced by the desaturases, SCD1-4 and the elongase, ELOVL6. In knock-out models, loss of SCD1 or ELOVL6 results in reduced Δ9 desaturated and reduced 18-carbon non-essential FA respec...
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