Cryogels from noble metal NPs have proven to be highly efficient catalysts due their high specific surface area which increases the mass transfer channels and catalytic active sites. By using oxides as co-catalysts, costs of material can significantly reduced, while activity remain same or even improve synergetic effects. In this work, we synthesize different cryogel thin films supported on mod...

This study proposes a molecular mechanism for lung epithelial A549 cell response to copper oxide nanoparticles (CuO-NPs) related to Cu ions released from CuO-NPs. Cells that survived exposure to CuO-NPs arrested the cell cycle as a result of the downregulation of proliferating cell nuclear antigen (PCNA), cell division control 2 (CDC2), cyclin B1 (CCNB1), target protein for Xklp2 (TPX2), and au...

Antimicrobial growth inhibition and mechanistic activities of synthesized Zinc oxide nanoparticles (ZnO NPs) were investigated in this study. Nanoparticle size 20-25 nm and concentrations of 0, 20, 40, 60, 80 and 100 μg/mL were used against pathogenic bacteria Staphylococcus aureus (Gram positive) and Salmonella typhimurium (Gram negative) and also first time against two plant fungi Aspergillus...

Protein adsorption onto nanoparticles (NPs) in biological fluids has emerged as an important factor when testing biological responses to NPs, as this may influence both uptake and subsequent toxicity. The aim of the present study was to quantify the adsorption of proteins onto TiO2 NPs and to test the influence on cellular uptake. The surface composition of the particles was characterized by th...

Lung exposure to metal oxide nanoparticles (NPs) comprising soluble metal haptens may produce T-helper cell type 1 (Th1)- and Th17-associated delayed-type hypersensitivity (DTH) responses and pulmonary alveolar proteinosis (PAP). In order to study this, haptenic metal oxide NPs (NiO, Co(3)O(4), Cr(2)O(3) and CuO) were instilled into the lungs of female Wistar rats, and the immunoinflammatory re...

We designed and synthesized several nanomaterials 3 of three-layered core-shell (γ-FeOx@AuNP)@[C60(>DPAF-C9) 1 or 2]n nanoparticles (NPs). These NPs having e(-)-polarizable fullerosome structures located at the outer layer were fabricated from highly magnetic core-shell γ-FeOx@AuNPs. Fullerosomic polarization of 3 was found to be capable of causing a large amplification of material permittivity...

The large-scale synthesis and the stabilization of noble metal nanocatalysts with ultrasmall sizes are crucial to their practical application. Herein, Pd, Au, Pt nanoparticles (NPs) in situ embedded on boron nitride nanosheets (BNNSs) via reduction precursor salts induced by 60Co γ-irradiation, which is a mature technique widely used industry. mechanism was elucidated pulse radiolysis experimen...

Recombinant human myelin basic protein (rhMBP) was previously produced in the milk of transgenic cows. Differences in molecular recognition of either hMBP or rhMBP by surface-immobilized anti-hMBP antibodies were demonstrated. This indicated differences in immunological response between rhMBP and hMBP. Here, the activity of free and controlled release rhMBP poly(ε-caprolactone) nanoparticles (N...

Zinc oxide nanoparticles (ZnO NPs), known for their chemical stability and strong adsorption, are used in everyday items such as cosmetics, sunscreens, and prophylactic drugs. However, they have also been found to adversely affect organisms; previously we found that ZnO NPs disrupt pubertal ovarian development, inhibit embryonic development by upsetting γ-H2AX and NF-κB pathways, and even distu...