Collective cell migration (CCM) is essential for organism development, wound healing, and metastatic transition, the primary cause of cancer-related death, and it involves cell-cell adhesion molecules of the cadherin family. Increased P-cadherin expression levels are correlated with tumor aggressiveness in carcinoma and aggressive sarcoma; however, how P-cadherin promotes tumor malignancy remai...

the dependence of some thermodynamic properties of spin-polarized liquid 3he such as velocity of sound, adiabatic index, isentropic compressibility and temperature on the spin polarization has been investigated along different isentropic paths. the lennard-jones potential has been used in our calculations. it has been found that for higher values of entropy, the spin polarization has greater ef...

Chitosan and randomly methylated β-cyclodextrin were the most to be studied absorption enhancers for nasal administration recently. The enhancing absorption mechanisms of each other were different. Authors chosen estradiol as the model drug used in situ and in vivo methods to study whether or not they could combine to enhance the nasal absorption. In situ study data indicated that the optimal c...

Introduction: Postoperative neurological deficit is the most devastating complication after thoracoabdominal aortic aneurysm repair. Despite demonstrated neuroprotective effects of estradiol, its protective efficacy against spinal cord ischemia-reperfusion and underlying mechanisms are not yet elucidated. Methods: Two groups, each of 10 New Zealand white male rabbits, were studied. Control g...

BACKGROUND The endometrium becomes receptive to the embryo after sequential actions of estrogen and progesterone. The purpose of this study was to examine the effects of estrogen and progesterone on endometrial hemodynamics and on secretion of vascular endothelial growth factor (VEGF) from endometrial epithelial cells (EEC). METHODS Six early postmenopausal women taking sequential estrogen an...

Nonylphenol (NP) is an endocrine disrupting chemical which has been shown to be able to modulate endocrine system of various organisms by different mechanisms. The objective of this study was to investigate the potential effects of  4-NP and 17-β-estradiol (E2) on immune parameters (IgM level and lysozyme activity) of   Koi carp (Cyprinus the carpio carpio)  in an attempt to expand the knowledg...

In this investigation, serum steroid hormones such as testosterone (T), 17β-estradiol (E2) and progesterone (P) in 12 female of the migratory population of Common carp (Cyprinus carpio) in southeast of Caspian Sea during a year from May 2011 to May 2012 were studied. The results of present study revealed that changes in levels of steroid hormones, (E2) and (T) were closely correlated to ovarian...