El objetivo de la presente investigación fue determinar influencia que ejercen los estilos crianza en depresión adolescentes escolarizados peruanos. Para ello, se utilizó una muestra 308 estudiantes nivel secundario, entre varones (47.1 %) y mujeres (52.9 %), tuvieron edad promedio 14.5 años (DE = 2.218). Tiene un diseño no experimental, empírico estrategia asociativa, clasificado dentro estudi...

Alzheimer's disease (AD), with a typical pathological hallmark of amyloid‑beta (Aβ)‑containing plaques and neurofibrillary tangles, is one of the most common types of chronic neurodegenerative diseases. Aβ oligomers serve a crucial role in the pathogenesis of AD, and lead to neuronal loss. However, the precise mechanism of Aβ oligomers in AD remains to be elucidated. The present study demonstra...

The progression of Alzheimer's disease is causatively linked to the accumulation of amyloid-β aggregates in the brain, however, it is not clear how the amyloid aggregates initiate the death of neuronal cells. The in vitro toxic effects of amyloid peptides are most commonly examined using the human neuroblastoma derived SH-SY5Y cell line and here we show that differentiated neuron-like SH-SY5Y c...

BACKGROUND β-blockers have little effectiveness in preventing vasovagal syncope in unselected populations, but they might be effective in older patients. We determined whether β-blockers prevent vasovagal syncope in an age-related fashion. METHODS AND RESULTS Two populations were studied. A proportional hazards analysis was performed on an observational cohort study of 153 patients with vasov...

The aim of this work was to study the effect of oxidative stress on the structural changes of the secondary peptide structure of amyloid beta 1-42 (Aβ 1-42), in the dentate gyrus of hippocampus of rats exposed to low doses of ozone. The animals were exposed to ozone-free air (control group) and 0.25 ppm ozone during 7, 15, 30, 60, and 90 days, respectively. The samples were studied by: (1) Rama...

Background The aggregation of tau hyperphosphorylation (p-tau) into neurofibrillary tangles (NFT) is a hallmark in the histopathology Alzheimer’s disease (AD). Our previous experiments found that β-asarone could prevent injury PC12 cells induced by A 1–42 , but it fight cell damage p-tau okadaic acid (OA) poorly understood. Objectives emphasis this study lies β-asarone’s therapeutical effect on...