Stability study of ceftazidime was realized in order to investigate kinetics of degradation of this drug both in powder for injection and reconstituted sample. Ceftazidime was submitted to conditions of accelerated thermal degradation and photodegradation. Analyses of the degraded samples were performed by microbiological assay and decomposition reactions could be described by zero-order and se...

A new mathematical model based on Michaelis Menten (MM) kinetics is developed to predict the changes in molecular weight distribution (MWD) during the enzymatic depolymerization of guar galactomannan. The model accounts for the effect of branching by considering the guar molecule as a substrate having three types of bonds with different MM kinetic parameters. The overall kinetics of the enzymat...

In this study, buccal mucoadhesive tablets of meloxicam were formulated for drug delivery as an alternative route. Direct compression method was applied for the preparation of tablets. Also, different polymers, including hydroxypropyl methyl cellulose (HPMC) 1000, 4000, and 10000, as well as carbopol 934p and carbopol 971p were used as the mucoadhesive polymer and retardant polymer. Thirteen fo...

BACKGROUND The objective of this research was to investigate the kinetic behavior of the biofil¬tration process for the removal of styrene. METHODS A three stage compost based biofilter was inoculated with thickened activated sludge. The reaction order rate constants were obtained from continuous experiments and used as the specific growth rate for the Monod equation. RESULTS The measured c...

In this study, buccal mucoadhesive tablets of meloxicam were formulated for drug delivery as an alternative route. Direct compression method was applied for the preparation of tablets. Also, different polymers, including hydroxypropyl methyl cellulose (HPMC) 1000, 4000, and 10000, as well as carbopol 934p and carbopol 971p were used as the mucoadhesive polymer and retardant polymer. Thirteen fo...

Hydrogel based tablets of Simvastatin was formulated using hydropropyl methyl cellulose(different grades), guar gum and carbopal-934-P with the aim to study of release kinetic, to attain a near zero order release and to increase the bioavalability upto 95%. In-vitro dissolution studies were carried out using USP type 2 dissolution test apparatus. The release of drug followed a typical Higuchian...

Kinetic investigations on Pd(II) catalyzed oxidation of D-ribose and D-arabinose by acidic solution of chloramine-T in the presence of mercuric acetate, as a scavenger have been made in the temperature range of 30°-45°C. The rate shows first order kinetics in case of chloramine-T and order of reaction is zero and one with respect to substrate and Pd(II) respectively. Increase in [Cl] showed pos...

the release of fe from soil solid phases into soil solution is a dynamic process that regulates the continuous supply of this element to growing plants. to ascertain the pattern of fe release, the kinetics of fe release from six soils by diethylenetriaminepentaacetic acid (dtpa) solution were investigated using soil samples taken from two different agroclimatic regions of iran. all soils were c...

A new binary polymer matrix tablet for oral administration was developed. The system will deliver drug at variable rates according to zero-order kinetics for total drug content and is manufactured by direct compression technology. Highly methoxylated pectin and hydroxypropyl methylcellulose (HPMC) at different ratios were used as major formulation components, and prednisolone was used as the dr...