The title compound, C(11)H(16)O(7), was obtained from the breakage reaction of the glycosidic bond of 5'-de-oxy-2',3'-diacetyl-inosine. The ribofuran-ose ring has a C2-exo, C3-endo twist configuration. No alteration of the relative configuration compared with d-(-)-ribose is observed.

The binding of labeled erythropoietin (EP) to cell surface receptors and subsequent processing of the hormone within the cell was studied in erythroid cells procured from the spleens of mice infected with the anemia strain of Friend virus. These immature erythroid cells respond to EP in culture to differentiate into reticulocytes and erythrocytes. Radiolabeled EP (both iodinated and tritiated) ...

We present a theoretical and numerical investigation of the effect of a timevarying external driving force on interface growth. First, we derive a relation between the roughening exponents which comes from a generalized Galilean invariance, showing how the critical dimension of the model is tunable with the external field. We further conjecture results for the exponents in two dimensions, and f...

The prostanoid receptors on human airway smooth muscle cells (HASMC) that augment the release by IL-1beta of granulocyte colony-stimulating factor (G-CSF) have been characterized and the signaling pathway elucidated. PCR of HASM cDNA identified products corresponding to EP(2), EP(3), and EP(4) receptor subtypes. These findings were corroborated at the protein level by immunocytochemistry. IL-1b...

Expressions involving the product of the permanent with the (n − 1)st power of the determinant of a matrix of indeterminates, and of (0,1)-matrices, are shown to be related to an extension to odd dimensions of the Alon-Tarsi Latin Square Conjecture, first stated by Zappa. These yield an alternative proof of a theorem of Drisko, stating that the extended conjecture holds for Latin squares of odd...

Parabens are widely used as preservative substances in foods, pharmaceuticals, industrial products, and cosmetics. But several studies have cautioned that parabens have estrogenic or endocrine-disrupting properties. Drosophila melanogaster is an ideal model in vivo to detect the toxic effects of chemistry. The study was designed to assess the potential additive toxic effects of methylparaben (M...

We define a new algebraic form for Boolean function representation, called EXOR-Projected Sum of Products (EP-SOP), consisting in a four level network that can be easily implemented in practice. Deriving an optimal EP-SOP from an optimal SOP form is a NP NP -hard problem; nevertheless we propose a very efficient approximation algorithm, which returns, in polynomial time, an EP-SOP form whose co...

Morbidity and mortality of the infected patients by multidrug-resistant bacteria have increased, emphasizing urgency fight for discovery new innovative antibiotics. In this sense, natural products emerge as valuable sources bioactive compounds. Among biodiversity, Eryngium pristis Cham. & Schltdl. (Apiaceae Lindl.) is traditionally used to treat thrush ulcers throat mouth, diuretic emmenago...

The dependence of the fractal behaviors of the pomeron induced system in deep inelastic lepton-nucleon scattering upon the diffractive kinematic variables is found not to sensitive to the distinct parameterization of the pomeron flux factor and the structure function. A feasible experimental test of the phenomenological pomeron model in DESY ep collider HERA is proposed.

A pharmacokinetics and metabolism study was conducted in eight healthy human volunteers. After oral administration of [14C]eplerenone (EP) at a dose of 100 mg per person as an aqueous solution, blood, saliva, breath, urine, and fecal samples were collected at various time points. All matrices were analyzed for total radioactivity and/or for EP and its open-lactone-ring form (EPA). EP was well a...