Fluorescence live imaging has become an essential methodology in modern cell biology. However, fluorescence requires excitation light, which can sometimes cause potential problems, such as autofluorescence, phototoxicity, and photobleaching. Furthermore, combined with recent optogenetic tools, the light illumination can trigger their unintended activation. Because luminescence imaging does not ...

Sarcoidosis is a multisystemic, inflammatory disease of unknown aetiology that is characterized by noncaseating granulomas. While numerous organs may be involved, the lungs, lymph nodes, and skin are most commonly affected. Therefore, in recent years dermoscopy is gaining appreciation in the era of inflammatory skin diseases such sarcoidosis, it allows better visualization of dermal vascular st...

In recent years, it has been recognized that bacteria can produce antibiotics of wide structural diversity. Many examples for the production of the antibiotics knownas products of Actinomycetales by eubacteria have been reported1*. Here, we will report the isolation of azomycin from the culture broth of a strain identified as Pseudomonas fluorescens. Azomycinwas first isolated from a strain res...

Strongly solvatochromic fluorophores are devised, containing alkyl chains and enable to self-assemble as very bright fluorescent organic nanoparticles (FONs) in water (Φf = 0.28). The alkyl chains impart each fluorophore with strongly hydrophobic surroundings, causing distinct emission colors between FONs where the fluorophores are associated, and their disassembled state. Such color change is ...

Once soluble in bile, bilirubin is transported through the biliary and cystic T he word “jaundice” comes from the French word jaune, which means yellow. Jaundice is a yellowish staining of the skin, sclera, and mucous membranes by bilirubin, a yellow-orange bile pigment. Bilirubin is formed by a breakdown product of heme rings, usually from metabolized red blood cells. The discoloration typical...

CASE REPORT A 28-year-old man (patient A) and a 46-year-old female (patient B) were diagnosed as having adenocarcinoma of the lung and received docetaxel chemotherapy to substitute previous regimen (gemcitabine and cisplatin) due to poor response. No significant adverse effects noted until the fourth cycle of docetaxel treatment, both patients developed nail changes. Both had acute nail pain fo...

Understanding the causes of variation in feather colour in free-living migratory birds has been challenging owing to our inability to track individuals during the moulting period when colours are acquired. Using stable-hydrogen isotopes to estimate moulting locality, we show that the carotenoid-based yellow-orange colour of American redstart (Setophaga ruticilla) tail feathers sampled on the wi...

Cytological and cytochemical studies of green monkey kidney cells infected with SV40 virus indicated that the type of lesion produced was influenced by the multiplicity of infection and that the lesions appeared later and progressed more slowly when the inoculum was diluted. The earliest change consisted of enlargement of ribonucleoprotein-containing spherules in the nucleolus (nucleolini). Thi...

Abstract Stone blocks, such as marble, granite, and sandstone, are natural materials with excellent properties. The most important dimension stone in Romania is Ruschita a known for its resistance to wear ability maintain beauty, regardless of colour. Regarding colour palette, marble stands out quality suit even the demanding requirements. It available shades yellowish, orange, pale pink or pin...