Hyperuricemia is a risk factor for gout and other cardiovascular diseases. One of the therapies used Allopurinol. Unfortunately, it has unwanted side effects. These conditions made researchers continue to seek develop alternative treatments from natural products. which plants Phyllanthus genus. their contents was polyphenols, especially flavonoids. It an treatment hyperuricemia because its mini...

A comparative study of lipid peroxidation and antioxidant potential has been made in human uterus and uterine tumor. Two types of uterine tumor used are: tumor (I), a fibroid which is the commonest benign solid tumor in uterus and tumor (II), an adenomyoma. Tumor microsomes are less susceptible to lipid peroxidation induced by both enzymic (NADPH-ADP-Fe3+ and xanthine-xanthine-oxidase) and non-...

BACKGROUND In this study, Salvia verbenaca L. aerial part extracts (SVEs): were screened for their antihemolytic, xanthine oxidase (XO) inhibition, antioxidant and antimicrobial activities. MATERIAL AND METHODS To investigate SVEs antihemolytic activity, the 2,2,-azobis (2-amidinopropane) dihydrochloride (AAPH) was used to induce erythrocyte oxidative hemolysis. In XO inhibition test, xanthin...

BACKGROUND Impaired flow-dependent, endothelium-mediated vasodilation (FDD) in patients with chronic heart failure (CHF) results, at least in part, from accelerated degradation of nitric oxide by oxygen radicals. The mechanisms leading to increased vascular radical formation, however, remain unclear. Therefore, we determined endothelium-bound activities of extracellular superoxide dismutase (ec...

Choerospondias axillaris Roxb. (Anacardiaceae) is a deciduous tree, native to Nepal and the Himalayan region, that can reach maximum height of 20 m. The study aimed assess total phenol, flavonoid, carbohydrate content, preliminary antioxidant potency, xanthine oxidase inhibition, antibacterial properties C. fruits extracts. Ethyl acetate, acetone, methanol, water were used as extraction solvent...

      Flavonoids could serve as potent inhibitors of xanthine oxidase (XO). In the present study, the effects of Ruta graveolens L. extract and its major isolated flavonoids, quercetin and rutin, on guinea pig liver XO have been investigated. The inhibitory effects of R. graveolens, quercetin and its glycoside form, rutin, were assayed spectrophotometrically. R. graveolens...

This study was conducted to search for xanthine oxidase (XO) inhibitors from the root extracts of Tamus communis L. traditionally used in folk medicine in Algeria. Root extracts with different solvents were screened for purified milk xanthine oxidase inhibition. The root extracts (methanol, chloroform and ethyl acetate) and proteins, obtained in distilled water, inhibited bovine, sheep and huma...

A comprehensive in vitro study involving antiglycation, antioxidant and anti-diabetic assays was carried out in mature fruits of strawberry. The effect of aqueous extract of mature strawberry fruits on glycation of guanosine with glucose and fructose with or without oxidizing entities like reactive oxygen species was analyzed. Spectral studies showed that glycation and/or fructation of guanosin...