OBJECTIVE To compare the wound healing rate and incidence of infection in wounds treated with either a bioactive dressing (containing hydrophilic mucopolysaccharide, chitosan) or conservative treatment (gauze). METHOD Eighty-five patients with diabetic foot ulcers, pressure ulcers or leg ulcers were randomised to receive either the bioactive study dressing (n=33 patients, 45 wounds) or the co...

Six pigs were used to evaluate the influence of three separate modalities on contaminated wounds. Full-thickness skin wounds on the abdomen were contaminated with 10(4) or 10(5) Staphylococcus aureus and then closed with one of three methods. The three closure modalities included (1) a new absorbable staple (Insorb) placed in the subcuticular tissue, (2) a braided Vicryl suture, and (3) percuta...

Whatever the etiology of wounds, some heal without difficulties, however in chronic wound ultimate goal wounds healing are to control symptoms and prevent complication like infection. The latter occurs when microorganisms different kinds grow within damaged skin. sign vary according type, severity infection immune system, generally simple can be treated at home. However medical attention should...

Wound infections are a serious medical problem for patients with non-healing chronic wounds and burn injuries. The healing of these wounds is often compromised by colonisation of many different bacteria, predisposing patients to life-threatening infections. Infected wounds continue to represent a complex problem for both health professionals and patients. Bacterial infections are a critical com...

Wound healing is an intricate process that requires complex coordination between many cell types and an appropriate extracellular microenvironment. Chronic wounds often suffer from high protease activity, persistent infection, excess inflammation, and hypoxia. While there has been intense investigation to find new methods to improve cutaneous wound care, the management of chronic wounds, burns,...

The fungus Fusarium circinatum Nirenberg and O’Donnell (Hypocreaceae) causes pitch canker, a disease affecting pines worldwide. In California, many native insect species have been implicated in transmission of F. circinatum. This study showed that two twig beetle species, Pityophthorus setosus Blackman and Pityophthorus carmeli Swaine (Coleoptera: Curculionidae: Corthylini), can make wounds on ...

OBJECTIVE Autologous platelet rich plasma is an advanced wound therapy used in hard-to-heal acute and chronic wounds. To better understand the use and clinical outcomes of the therapy, a systematic review of the published literature in cutaneous wounds was performed. METHODS Electronic and hand searches for randomized controlled trials and comparative group studies using platelet rich plasma ...

In a randomized trial of wound closure in 512 abdominal wounds, wounds were closed with either reinforced Steristrip skin closures or interrupted silk sutures. Comparisons were made of wound pain and discomfort, wound infection, discharge, redness, width, and skin reaction. The causes of peeling of the tapes were assessed. The results showed that tapes were significantly more comfortable and th...

Patients with burns and wounds are more likely to contract an infection in the hospital than other patients due loss of protective barrier (skin) immune system disorders that appear these patients, making affected tissues a suitable environment for infection. Hospital is one most severe complications affect significantly increases rates disease death. Burn wound infections frequently harbor bac...

OBJECTIVE To compare standard management of keeping wounds dry and covered with allowing wounds to be uncovered and wet in the first 48 hours after minor skin excision. DESIGN Prospective, randomised controlled, multicentre trial testing for equivalence of infection rates. SETTING Primary care in regional centre, Queensland, Australia. PARTICIPANTS 857 patients randomised to either keep t...