Background Acute postoperative pain is induced by most incisional surgeries and usually resolves with wound repair. However, many patients experience moderate to severe pain despite receiving currently available postoperative pain relief. Accumulating evidence suggests that inflammatory cells, neutrophils, and macrophages infiltrating the wound site contribute to the acute inflammation, pain, a...

OBJECTIVES Compare circular defect with dog-ear deformities excision (CDDE) technique to 3:1 fusiform excision technique when removing facial lesions to analyze which technique provides superior wound closure. METHODS Identical 1-cm circular skin defects were created on bilateral cheek, forehead, and parietal scalp on three fresh cadavers. Similarly, using four fresh cadavers, identical 2-cm ...

Wound healing activity of methanolic extract of leaves of Alternanthera brasiliana Kuntz was studied by excision and incision wound model (in vivo) in Sprague Dawley rats and by Chorioallantoic membrane (CAM) model (In vitro) in 9-day-old embryonated chicken eggs. In excision wound model, compared to the control group, per cent contraction of wound was significantly higher in A. brasiliana (5% ...

To screen the wound healing activity of different extracts of Allium cepa L. in excision, incision and dead space wound models in albino rats. The tubers of Allium cepa L. (Family Liliaceae) were exhaustively defatted with petroleum ether (40-60C) and the marc was subjected to continuous extraction with solvent ether, chloroform, alcohol and chloroform water I.P. All the extracts were tested fo...

The different extracts of the bark of Tecoma stans Linn. (Bignoniaceae) was evaluated for its wound healing potential in two different types of wound models in albino rats viz., incision and excision. The different extracts of Tecoma stans are obtained by successive soxhlet extraction with petroleum ether, chloroform and methanol. The methanolic extract showed significant increase in wound cont...

OBJECTIVE We wished to determine the reduction in the rate of wound complications that would render the use of prophylactic negative pressure wound vacuum therapy (NPWT) cost saving compared to routine incision care (RC) following laparotomy for gynecologic malignancy. METHODS A decision tree was designed from a payer perspective to compare strategies for incision management following laparot...

Solanum xanthocarpum Schrad. & Wendl. (Family-Solanaceae), commonly known as Yellow-Berried Nightshade, fruits are used traditionally in the folklore for treatment of various kinds of wounds. The present study was undertaken to verify the effects of its fruits on experimentally induced excision and incision wound models in Sprague Dowlay rats. Aloe vera Linn. was used as standard wound healing ...

case presentation we report a case where a substantial right ovarian cyst in a 13 year old was removed through a single incision in the superior umbilical fold leaving no discernable scar. the placement of a purse string facilitated safe decompression of the cyst allowing delivery into the wound where the lining was stripped before being returned to the abdomen. conclusions subsequent single in...

OBJECTIVE To evaluate the wound healing potential of fractions from ethanol extract of Martynia annua (M. annua) Linn leaves. METHODS Ethanol extract of M. annua Linn leaves was fractionate into three different fractions (MAF-A, MAF-B and MAF-C) which were screened for wound healing potential using two models: excision and incision on rats. The thin layer chromatography (TLC) profile of all f...