Aims and objectives :To study the effects of topical Ripasudil on diabetic macular edema in tertiary eye care hospital. Materials Methods:: Ethics approval was obtained. Written informed consent It is a prospective interventional 20 eyes (10 as controls,10 tests) presenting to our opd. Inclusion criteria for patients whom ripasudil administered are with DME FT->300µm no history ocular surge...

The influence of the semisynthetic epipodophyllotoxin derivative VP 16-213 on different cellular and biochemical parameters was determined with the use of suspension cultures of a murine mastocytoma. Cells were exponentially dividing and not synchronized. Treatment with VP 16-213 (l ¿ig/ml) reduced the mitotic index by more than 75% within 1.5 hr and completely prevented cell multiplication up...

The effects of temperature on skin papillomas of newts (Cy nops pyrrhogaster) were studied. Newts bearing these tumors were maintained for 30 weeks at 4 ±1 (S.E.), 10 ±1,13 ±2, 25 ±1, and 30 ±1°.The diameters of the papillomas were measured externally. They decreased at 4, 25, and 30°, and increased at 10 and 13°.The effect of temperature on the tumor growth or regression began to appea...

â  â  â  â  narration elements in the story of mousa and khezr â  (based on character and time) â  â  sayyed reza solayman zadeh najafi * â  azim tahmasbi ** â  â  abstract â  â  the story consists of elements such as character and time and the story features. characters make story’s structure and there is not story without character . time element is also necessary for the story . each story...

Genomic DNA was extracted from archival pathology specimens comprising 10 squamous and 14 adenocarcinomas, including 7 with Barrett's epithelium adjacent to tumor, and corresponding normal esoph agus from the resection margin. The polymerase chain reaction was used to amplify selected exons ofp53 which were analyzed for mutations using single-strand conformation polymorphism analysis. Mutations...

Freshly isolated Morris Hepatoma 7777 cells were prepared for a study of the utilization of palmitate and 0-hydroxybulyrale as metabolic fuels compared to other major energy substrates (glucose and glutamine). These cells were capable of oxidizing both |i/-'4C]palmilale and 0[3-'4C]hydroxybutyrate although the rates accounted for only 10 ±3 (SD) and 9 ±4% of total oxygen consumed, respectivel...

A general procedure is presented for calibrating a model for rainfall erosivity based on daily rainfall. The approach is based on probability distributions of wet-day precipitation amount and monthly erosivities which are inferred from published data summaries. The calibrated model was tested by comparisons with erosivities computed from hourly precipitation data. Model results were generally c...

Based on long-term rainfall measurements (1956-2012), water level records (1956-2006), and aquatic plants field survey data (1960-2014), the relationship between precipitation and aquatic vegetation succession in east Taihu Lake, China, is studied. Neither abrupt changes nor any trends were found in the annual rainfall series in Taihu Lake during the studied period (1956-2012). However, for sea...

INTRODUCTION Several differing strains of mice have been pro duced from the NHO stock (7) as a result of sib inbreeding associated with repeated subcutaneous injections of methylcholanthrene. One of these strains, Br-S, is characterized by a high incidence of gastric adenomas or adenocarcinomas. The cvi dence for a hereditary basis of the abnormality is extensive (7—10). However, the etiology...