The aim of this work was to study the effect a high fat and carbohydrate diet (HFCD) quercetin supplementation on levels dopamine (DA), serotonin (5-HT) their metabolites in Wistar, DA transporter knockout (DAT-KO) obese Zucker fa/fa rats. Animals received control or HFCD for 62 days. Wistar rats quercetin. contents DA, 5-HT, norepinephrine (NE), dioxyphenyl acetate (DOPAC), homovanillic acid (...