Ethylene glycol (EG)-induced hyperoxaluria is the most commonly employed experimental regimen as an animal model of calcium oxalate (CaOx) stone formation. The variant sensitivity to CaOx among different rat strains has not been fully explored, although the Wistar rat is known to accumulate more CaOx in kidney tissue after low-dose EG exposure than in the Fischer 344 (F344) rats. Supersaturatio...

3 Jing-Wu Liu 1 4 Physical Oceanography Laboratory, and Ocean–Atmosphere Interaction and Climate 5 Laboratory, Ocean University of China, Qingdao, China 6 7 Shang-Ping Xie 8 Scripps Institution of Oceanography, University of California, San Diego, La Jolla, 9 California; 10 International Pacific Research Center and Department of Meteorology, School of Ocean 11 and Earth Science and Technology, ...

The effects of severe protein malnutrition (4%) on myenteric neurons of Wistar rat duodenum, in relation to a standard 22%-protein diet for rodents, were assessed in this study. Segments of the duodenum from 10 rats from each nutritional group were submitted to the elaboration of whole mounts - 5 stained with Giemsa to determine the total population of myenteric neurons and the others stained b...

Compared with the normotensive Wistar-Kyoto rat, the spontaneously hypertensive rat exhibits exaggerated alterations in renal sympathetic nerve activity and excretory function during volume expansion (exaggerated natriuresis) and environmental stress (antinatriuresis). The borderline hypertensive rat is the first filial offspring of the spontaneously hypertensive rat and the Wistar-Kyoto rat an...

Grace V. O’Donovan, Houdini H.T. Wu, Oona Y-C. Lee, Ramasamyiyer Swaminathan, Graham F. Cope and Heather J. Milburn Dept of Respiratory Medicine, Mayday University Hospital, Croydon, Dept of Biochemistry, Guy’s and St Thomas’ NHS Foundation Trust, London, King’s College London School of Medicine, University of London, London, Dept of Respiratory Medicine, Guy’s and St Thomas’ NHS Foundation Tru...

This study examines strain differences in testosterone (T)-hydroxylations between Wistar and Dark Agouti (DA) rats of both genders. The DA rat, an animal model, is a poor metabolizer of such drugs as debrisoquine, which are metabolized by cytochrome P450 (CYP) 2D. T-16α-, 2α-hydroxylations, which are linked to CYP2C11, were catalyzed at similar rates by the microsomes of both strains. In contra...

We tested the hypothesis that a genetically determined increase in renal or-adrenergic receptor density might be a pathophysiologically important factor in the spontaneously hypertensive rat model of genetic hypertension. In a first study, we compared renal a,and <*t-adrenergic receptor density with systolic blood pressure in 45 rats of an F2 generation of Wistar-Kyotox spontaneously hypertensi...

Article history: Received on: 08/11/2012 Revised on: 29/11/2012 Accepted on: 15/12/2012 Available online: 28/01/2013 In this study, assessment of the potential effect of cypermethrin-treated lettuce on the rat liver physiology is carried out. Cypermethrin-treated lettuce and three doses of cypermethrin (CY) were administered during 28 days to rats. Along the experimental period, animal behavior...

OBJECTIVE(S) The effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study. MATERIALS AND METHODS Male Wistar rats were randomly divided into control sedentary (C), moderate trained (MT), (V=20 m/min, 30 min/day for 6 days a week, 8 weeks), overtrained (OT) (V=25 m/min, 60min/day for 6 days a week, 11 weeks) and recovered overtrained (OR) (...

For Quantitative Detection Using Electrical Impedance Spectroscopy Cheng-Hsin Chuang, Deng-Maw Lu, Lung-Yu Chang, Kai-Chieh Chang, Cheng-Ho Chen, Ting-Feng Wu, Muhammad Omar Shaikh and Hsun-Pei Wu Depart. of Mechanical Eng., Southern Taiwan University of Science and Technology, Tainan, Taiwan Depart. of Chem. and Mater. Eng., Southern Taiwan University of Science and Technology, Tainan, Taiwan ...