Testing a sequence of pre-ordered hypotheses to decide which of these can be rejected or accepted while controlling the familywise error rate (FWER) is of importance in many scientific studies such as clinical trials. In this paper, we first introduce a generalized fixed sequence procedure whose critical values are defined by using a function of the numbers of rejections and acceptances, and wh...

We propose an algorithm for the migration of cloud applications’ components between different providers, possibly changing their service level between IaaS and PaaS. Our solution relies on three of the key ingredients of the trans-cloud approach: a unified API, agnostic topology descriptions, and mechanisms for the independent specification of providers. We show how our approach allows us to ov...

There are various methods for obtaining the preference vector of pair-wise comparison matrix factors. These methods can be employed when the elements of pair-wise comparison matrix are crisp while they are inefficient for fuzzy elements of pair-wise comparison matrix. In this paper, a method is proposed by which the preference vector of pair-wise comparison matrix elements can be obtained even ...

2 Methods 5 2.1 Multiple hypothesis testing framework . . . . . . . . . . . . . 5 2.2 Test statistics null distribution . . . . . . . . . . . . . . . . . 11 2.3 Single-step procedures for control of general Type I error rates θ(FVn) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 2.4 Step-down procedures for control of the family-wise error rate 16 2.5 Augmentation multiple tes...

We consider a clinical trial with a primary and a secondary endpoint where the secondary endpoint is tested only if the primary endpoint is significant. The trial uses a group sequential procedure with two stages. The familywise error rate (FWER) of falsely concluding significance on either endpoint is to be controlled at a nominal level α. The type I error rate for the primary endpoint is cont...

background china is a country with a high prevalence of hepatitis b. as a special population, migrant workers are more vulnerable to hepatitis b. objectives the present study was conducted to gain insight into the prevalence of hepatitis b and knowledge about hepatitis b among migrant workers in shandong province, china, as well as to explore a series of strategies for preventing and controllin...