Skeletal metastasis is one of the most important disabling complications of the malignant diseases. As in general, the survival of patients with osteometastatic lesions is relatively long, an early diagnosis can lead to improve the patient’s life, both quantitatively and qualitatively, and prevent exacerbation of the disease and disabling complications. In this study, 22 patients with est...

skeletal metastasis is one of the most important disabling complications of the malignant diseases. as in general, the survival of patients with osteometastatic lesions is relatively long, an early diagnosis can lead to improve the patient’s life, both quantitatively and qualitatively, and prevent exacerbation of the disease and disabling complications. in this study, 22 patients with establish...

Serum thyroglobulin (Tg) and Tg antibody (TgAb) levels, together with neck ultrasonography and 131I whole-body scintigraphy (WBS), are diagnostic tools for postoperative follow-up of patients with differentiated thyroid carcinoma (DTC). Generally, good correlation is seen between Tg and WBS in follow-up studies for DTC after thyroid remnant ablation. Undetectable serum Tg with negative WBS resu...

Iodine-131 (131I) plays an important role in the management of patients with well-differentiated thyroid cancers. Post-thyroidectomy ablation therapy with 131I is performed to destroy the small amount of thyroid tissue remaining in the neck after surgery [8,14]. The use of radioiodine for ablation has been shown to decrease the risk of recurrence, increase the sensitivity of post-ablation whole...

OBJECTIVE Tc-methoxyisobutyl isonitrile (MIBI) has been reported to show considerable clinical utility in the study of many neoplastic diseases. The aim of our study was to investigate the possible role of Tc-MIBI in the initial follow-up of patients with differentiated thyroid cancer (DTC) for detecting residual thyroid uptake and/or loco-regional/distant metastases. METHODS Eighty-two patie...

Thyroid hormone withdrawal (THW) for postoperative radioiodine adjuvant therapy or diagnostic radioiodine whole body scan in patients with differentiated thyroid cancers results in acute thyroid hormone deficiency and abnormal lipid profiles. To better clarify the clinical pattern of dyslipidemia occurring after THW, we retrospectively analyzed the association between serum total cholesterol le...

Abstract Background Radioactive iodine 131 (I-131) is used in the treatment of differentiated thyroid cancer after thyroidectomy; however, its accumulation non-thyroidal regions may give false positive results on whole body scan (WBS). Only a few cases radioiodine uptake orbital region patients with have been reported, which could be due to metastasis or causes resulting from contamination infl...

Whole-body metastatic sun•ey scans are performed in order to determine the extent of metastases, the quality of tumor uptake, and whether the patient will benefit from therapeutic doses of radioiodine. Periodic whole-body scans also help to evaluate the success of radioiodine therapy or the necessity to repeat therapeutic treatments. Using a dual-probe rectilinear scanner and supplementing with...

conclusions: this study provides detailed information and case samples of radiodine contamination artifacts and non-physiological, non-metastatic extra-thyroidal i-131 accumulation in whole-body i-131 imaging. introduction: radioactive iodine has been used for more than 50 years for the treatment of thyroid diseases. differentiated thyroid cancers have the ability to trap iodine. therefore, rad...