A 25-year-old woman had total thyroidectomy and iodine-131 ablation therapy for papillary thyroid carcinoma. Whole body imaging on the 7th day of therapeutic activity demonstrated radioiodine uptake in the remnant tissue and intense heterogeneous uptake at the sacral region prominently in the posterior image. Initial interpretation was suspicious for sacral metastasis. Technetium-99m-methylene ...

introduction: ubiquicidin (ubi) 29-41 is a synthetic antimicrobial peptide that binds with the microbial cell membrane at the location of infection. this study was conducted to evaluate its probable efficacy as an infection-imaging agent with potential to differentiate bacterial infection from sterile inflammation in humans. methods: fifteen diabetic foot patients (10 males and 5 females) with...

PURPOSE 99mTc-3PRGD2, a promising tracer targeting integrin receptor, may serve as a novel tumor-specific agent for single photon emission computed tomography (SPECT). A multi-center study was prospectively designed to evaluate the diagnostic accuracy of 99mTc-3PRGD2 imaging for bone metastasis in patients with lung cancer in comparison with the conventional 99mTc-MDP bone scan. METHODS The p...

Post-treatment or diagnostic whole-body radioiodine scintigraphy is widely used to assess the residual, recurrence, or metastases of differentiated thyroid carcinoma because of the high sensitivity and accuracy that this assessment provides. While bearing in mind all the diagnostic potential of this test, we have to consider its’ potential pitfalls, as well. Herein, we present 4 patients with d...

Intracortical hemangioma is an extremely uncommon primary bone tumor; only 11 cases have been reported in the English literature. We report a case of right tibial intracortical hemangioma with pathologic and imaging findings, including plain radiograph, MRI, and whole-body bone-scan images.

A 76-year-old man with bone metastases of prostate cancer diagnosed a year ago was admitted for relief of bone pain (visual analogue scale: 90%) most markedly in cervical spine and upper extremities due to skeletal metastases. His serum prostate specific antigen level was markedly increased (351 ng/ml). After documentation of sufficient tracer uptake in multiple bone metastases on whole-body 99...

Received 5/18/2006; revised 6/23/2006; accepted 6/26/2006. For correspondence or reprints contact: Ming-Hsien Lin, M.D., Department of Nuclear Medicine, Taipei City Hospital, Zhongxiao Branch. 87 Tong De Road, Nan Gang District, Taipei 115, Taiwan. Tel: (886)2-27861288 ext. 8089, Fax: (886)2-26534501, E-mail: [email protected] The numb chin syndrome (NCS), also referred to as mental neuropathy...

Tc-99m-methylene diphosphonate (MDP) whole body scintigraphy is the method of choice for detection of metastatic bone diseases. It is primarily used to help diagnose various bone-related conditions such as primary or metastatic cancer of the bone, location of bone inflammation, and fractures that may not be visible on traditional X-ray images, as well as detection of bone damage due to infectio...