To evaluate the role of electrophilicity in the induction of allergic contact dermatitis (ACD) in humans, we compared the structure-activity relationship (SAR) model of ACD with those of electrophilic and nonelectrophilic subsets of chemicals in the ACD database. For these analyses, electrophilicity was defined as the potential of a chemical to induce mutations in Salmonella. It was found that ...

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The widespread use of contact lenses is associated with several complications, including ocular biofilm-related infections. They are very difficult to manage with standard antimicrobial therapies, because bacterial growth in a biofilm is associated with an increased antibiotic resistance. The principal aim of this study was to evaluate the efficacy of antimicrobial peptides (AMPs) in eradicatio...

methyl methacrylate (mma), a widely used monomer in dentistry and medicine has been reported to cause abnormalities or lesions in several organs. experimental and clinical studies have documented that monomers may cause a wide range of adverse health effects such as irritation to skin, eyes, and mucous membranes, allergic dermatitis, stomatitis, asthma, neuropathy, disturbances of the central n...

purpose: to evaluate the prevalence of contat lens wear among highschool girls and their general knowledge about contact lenses and also to evaluate the specific knowledge of contact lens wearers about the lens. methods: in a cross-sectional study, 1664 students of 22 randomly selected girl highschools were enrolled. a questionaire including questions about wearing contact lens, age of first us...

We describe a wink-controlled hands-free switching system for eye-borne telescopic vision, based on a previously tested fixed-magnification telescope embedded within scleral contact lenses. Here we integrate orthogonal polarizers into the contact lens covering the F/9.1 refractive 1× and F/9.6 catadioptric 2.8× vision paths, to allow switching via external liquid crystal shutters. We provide ha...

PURPOSE To evaluate ocular response and subject acceptance of a new multipurpose disinfecting solution (MPDS), Complete Revitalens (RevitaLens OcuTec in the US Market), for soft contact lens care in a large "real practice" setting. METHOD This is an international multi-center, open-label assessment carried out in 10 countries across Europe and in the USA. Up to 10 subjects who were currently ...

this study was conducted to examine if allergic contact dermatitis (acd) alters the expression of mmps in human dermal fibroblasts. fibroblasts are the primary source for mmp and matrix production in skin. mmps are known to involve in a number of physiological and pathological processes. some published data indicated a gelatinase-like activity in acute and chronic phases of allergic contact der...

in this paper, finite element elastic contact analysis of a functionally graded (fg) hollow brake disk in contact with pad, subjected to rotation, contact pressure and frictional heat is presented. the material properties vary through the thickness according to a power-law characterised by a grading index, n. the material property is purely steel at the core part and gradually moves and approac...