Title of dissertation: STRUCTURAL CHARACTERIZATION OF METAL AND DNA BINDING TO DREAM PROTEIN, A CALCIUM SENSING TRANSCRIPTIONAL REPRESSOR IN PAIN MODULATION Aswani Kumar Valiveti, Doctor of Philosophy, 2006 Dissertation directed by: Dr. James. B. Ames Center for Advanced Research in Biotechnology DREAM (Downstream Regulatory Element Antagonistic Modulator) is the first reported calcium binding ...

Memory deficits in aging affect millions of people and are often disturbing to those concerned. Dissection of the molecular control of learning and memory is paramount to understand and possibly enhance cognitive functions. Old-age memory loss also has been recently linked to altered Ca(2+) homeostasis. We have previously identified DREAM (downstream regulatory element antagonistic modulator), ...

Since ancient times, in societies throughout the world, mankind has interpreted some dreams in the context of religion – from invoking the gods into their dreams in incubation temples, to recording dream narratives in holy scriptures of religions that thrive in today’s world. This paper acknowledges that the role of dreams has diminished in many faiths, most noticeably in western Christianity, ...

dream should be considered as a kind of cognitive ability that is formed parallel to other cognitive capabilities like language. on the other hand, multiple sclerosis (ms) is a complex disease that can involve different aspects of our cognition. therefore, ms may influence patients' dreams. in fact, we do not know what the importance of dream is in ms, but further studies may introduce dream an...

Control and treatment of chronic pain remain major clinical challenges. Progress may be facilitated by a greater understanding of the mechanisms underlying pain processing. Here we show that the calcium-sensing protein DREAM is a transcriptional repressor involved in modulating pain. dream(-/-) mice displayed markedly reduced responses in models of acute thermal, mechanical, and visceral pain. ...

This study investigates the cumulative effects of lifetime traumatization on dream activities and the extent to which potentially traumatic events, dream variables, and inhibitory functions can predict the severities of psychopathological symptoms. The sample consisted of 564 young adults, whose dream experiences, trauma history, ego functions, and symptom manifestations were assessed using the...

This study investigates evidence, from dream reports, for memory consolidation during sleep. It is well-known that events and memories from waking life can be incorporated into dreams. These incorporations can be a literal replication of what occurred in waking life, or, more often, they can be partial or indirect. Two types of temporal relationship have been found to characterize the time of o...

PURPOSE To explore the function of DREAM gene mediated by NF-kB signal pathway in the pathogenesis of osteosarcoma. METHODS This study included 13 Sprague Dawley (SD) rats with osteosarcoma (treatment group) and 13 healthy rats (control group). NF-kB, DREAM and P105 mRNAs expression levels were determined using quantitative PCR (qPCR). The expression levels of NF-kB, DREAM and P105 proteins w...

Dream incubation refers collectively to the practices, rituals, techniques and efforts that an individual applies to intentionally evoke helpful dreams. Derived from the Latin verb incubare (in'upon' + cubare 'to lie'), the term connotes the support and nurturance provided by a laying mother bird for her developing egg. The parallels with dream influence are all too appropriate; in antiquity, t...