background: constraint induced movement therapy is one of the new therapeutic interventions that limits the performance of intact upper limb with increased use of the affected limb. aim of this study was to investigate the effects of  modified constraint induced movement therapy on weight bearing & protective extension in children with hemiplegic cerebral palsy. methods: 21 hemiplegic children ...

A decrease in proteoglycan (Pg) content and disturbances in the collagen network have been reported in aging cartilage. This study aims to determine whether these changes are associated with proteolytic enzymes such as neutral metalloproteases. Eighty lateral tibial plateaus were collected from subjects after death. The age, topographical area, and lesion severity (macroscopic grading) of each ...

The acetone and ethanol extracts from the leaves of Sida Veronicaefolia i.e. AESV and EESV respectively were evaluated for antitumor activity against Ehrlich Ascites Carcinoma (EAC) bearing Swiss albino mice. The extracts were administered at the doses of 500 mg/kg body weight per day for 14 days after 24 h of tumor inoculation. 24 h after the last dose, with fasting, the mice were sacrificed. ...

Background: Physical activity has been recommended for the prevention and even treatment of osteoporosis because it potentially can increase bone mass and strength during childhood and adolescence and reduce the risk of falling in older populations. However, few reports have systematically investigated the effect of physical activity on bone in men and women of different ages. Purpose: The goal...

EFFECT OF BIOFEEDBACK DEVICES IN PARTIAL WEIGHT-BEARING ORTHOPAEDIC PATIENTS. Joshua W Hustedt, Michael R Baumgaertner, Michael P Leslie, Jonathan N Grauer. Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT. Partial weight-bearing (PWB) instructions are commonly given to orthopaedic patients. However, the ability of patients to comply with these in...

High impact physical activity (PA) is thought to benefit bone. We examined associations of lifetime walking and weight bearing exercise with accelerometer-measured high impact and overall PA in later life. Data were from 848 participants (66.2% female, mean age = 72.4 years) from the Cohort for Skeletal Health in Bristol and Avon, Hertfordshire Cohort Study and MRC National Survey of Health and...

Epidermal growth factor (EGF) receptor-binding peptides from the urine of tumor patients have been reported to differ in molecular weight and relative hydrophobicity from those of normal individuals. Nude rats bearing human large cell lung carcinomas or chondrosarcomas and non-tumor-bearing sibling control rats were used to investigate the contributions of tumor and host to urinary EGF-related ...

Host effects produced by the tumor were studied in rats with the Walker carcinoma 256 either contaminated with or free of Salmonella typhimurium. In the absence of bacterial infection, tumor growth caused slight changes in most of the systems studied. Usually the changes were most pronounced when the tumors were 10-15 per cent of the total body weight. In the presence of infection, the changes ...

BACKGROUND The rate of Achilles tendon ruptures is increasing, but there is a lack of consensus on treatment of acute injuries. The purpose of this trial was to compare outcomes of weight-bearing casts with those of traditional casts in the treatment of acute Achilles tendon ruptures. METHODS Eighty-four patients with an acute Achilles tendon rupture were recruited over a two-year period. Pat...