Background. Differentiating between schizophrenia and major depression with psychotic features often reveals diagnostic dilemma. Both share psychotic features and severe impairment in occupational functions. Severe psychomotor retardation, not uncommon in psychotic depression, may simulate negative symptoms of schizophrenia. Our work aims at utilizing Wisconsin Card Sorting Test (WCST) performa...

The present study represents the first large scale confirmatory factor analysis of the Wisconsin Card Sorting Test (WCST). The results generally support the three factor solutions reported in the exploratory factor analysis literature. However, only the first factor, which reflects general executive functioning, is statistically sound. The secondary factors, while likely reflecting meaningful c...

Little is known about the individual factors that predict outcomes in Internet-administered psychological treatments. We hypothesized that greater cognitive flexibility (i.e. the ability to simultaneously consider several concepts and tasks and switch effortlessly between them in response to changes in environmental contingencies) would provide a better foundation for learning and employing the...

OBJECTIVE To examine the association between functional haplotypes in the catechol-o-methyltransferase (COMT) gene and ADHD diagnosis, and executive function (EF) in children with ADHD. METHOD COMT single nucleotide polymorphism (SNPs; rs6269, rs4633, rs4818, and rs4680) were genotyped in 445 ADHD children. EF was assessed using Wisconsin Card Sorting Test (WCST), Tower of London, and self-or...

Adult age differences in Wisconsin Card Sorting Test (WCST) measures were examined before and after statistical control of age-related differences in measures of feedback usage, working memory, and perceptual-comparison speed. The proportion of age-related variance associated with a summary measure of WCST performance was greatly reduced after controlling for measures of feedback usage, working...

This study aimed to explore non-verbal executive processes in simultaneous interpreters. Simultaneous interpreters, bilinguals without any training in simultaneous interpreting, and control monolinguals performed the Wisconsin card sorting task (WCST; Experiment 1) and the Simon task (Experiment 2). Performance on WCST was thought to index cognitive flexibility while Simon task performance was ...

objective: the current study was performed to evaluate the cognitive improvements of the chronic schizophrenic patients treated with risperidone in comparison with those treated with haloperidol according to wisconsin card sorting test (wcst). methods: in a double blind clinical trial, 65 patients with a diagnosis of chronic schizophrenia were randomly allocated into two groups. they received a...

We examine online learning in the context of the Wisconsin Card Sorting Task (WCST), a task for which the concept acquisition strategies for human and other primates are well documented. We describe a new WCST experiment in rhesus monkeys, comparing the monkeys’ behaviors to that of online learning algorithms. Our expectation is that insights gained from this work and future research can lead t...

To explore the role of monoamines on cerebral function during specific prefrontal cognitive activation, we conducted a double-blind placebo-controlled crossover study of the effects of 0.25 mg/kg oral dextroamphetamine on regional cerebral blood flow (rCBF) as determined by 133Xe dynamic single-photon emission-computed tomography (SPECT) during performance of the Wisconsin Card Sorting Test (WC...

The specificity of the Wisconsin Card Sorting Test (WCST) as a marker of frontal lobe pathology remains controversial. One problem is the lack of a well established correspondence between WCST errors and specific cognitive or neural processes. The conventional scoring of non-perseverative WCST errors does not discriminate between errors related to the efficient test of hypotheses during set shi...